ChemicalBook > CAS DataBase List > Selank peptide

Selank peptide

Description

Product Name: Selank peptide
CAS No.: 129954-34-3
Chemical Name: Selank peptide
Synonyms: SLANK;Selanc;SELANK;PL14736;Selank CAS;Salbu Sulfate;Selank peptid;SelankAcetate;Selankamidate;Selank peptide
CBNumber: CB33161651
Molecular Formula: C33H57N11O9
Formula Weight: 751.87
MOL File: 129954-34-3.mol

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Selank peptide Property

Melting point:: 134-136 °C
Density: 1.53±0.1 g/cm3(Predicted)
pka: 3.43±0.20(Predicted)
Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
InChI: InChI=1S/C33H57N11O9/c1-19(45)26(35)29(49)41-20(8-2-3-13-34)30(50)44-17-6-11-23(44)28(48)40-21(9-4-14-38-33(36)37)31(51)43-16-5-10-22(43)27(47)39-18-25(46)42-15-7-12-24(42)32(52)53/h19-24,26,45H,2-18,34-35H2,1H3,(H,39,47)(H,40,48)(H,41,49)(H,52,53)(H4,36,37,38)/t19-,20+,21+,22+,23+,24+,26+/m1/s1
InChIKey: JTDTXGMXNXBGBZ-YVHUGQOKSA-N
SMILES: C(O)(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H]([C@H](O)C)N

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27720
Product name: Selank (acetate)
Packaging: 5mg
Price: $508
Updated: 2023/01/06

Cayman Chemical

Product number: 27720
Product name: Selank (acetate)
Packaging: 10mg
Price: $879
Updated: 2023/01/06

Cayman Chemical

Product number: 27720
Product name: Selank (acetate)
Packaging: 1mg
Price: $136
Updated: 2023/01/06

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Selank peptide Chemical Properties,Usage,Production

Description

Selank is a synthetic derivative of the tetrapeptide tuftsin that contains a proline-glycine-proline sequence at the C-terminus and has anxiolytic and anti-inflammatory activities. It increases the amplitude and discharge rate of inhibitory postsynaptic currents of neurons in the rat hippocampal CA1 region when used at a concentration of 1 μM. It decreases the level of affective responses and the number of erroneous escape attempts in rats in an acute stress situation, increases orientational-investigative responses of rats in an unfamiliar situation, and reduces the time mice spend immobile in the forced swim test. It increases locomotor activity of high-anxiety Balb/c, but not C57Bl/6, mice in the open field test. Selank (0.01 mg/kg) decreases verticalization induced by apomorphine in mice. It also decreases expression of the inflammation-related genes Il2rg and Xcr1 in mouse spleen after 90 minutes when administered at a dose of 100 μg/kg.

Uses

Selank peptide has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and antistress drug that relieves aggression and fear reaction in different animal species. It is often prescribed for its anxiolytic properties, immune improvement, gastric protection, and with opioid and alcohol withdrawal/ dependence. It also has a nootropic action, which positively influences the formation of memory and learning processes, and marked immunomodulatory activity.

benefits

Selank peptide has the following benefits: It improves anxiety and stress reactions. Enhances memory and learning. Strengthens immune function by increasing inflammatory proteins to help fight infections. Increases BDNF (brain-derived neurotrophicfactor) - a vital brain-growth compoundrelated to learning and memory. Prevent weight gain and reduce cholesterol. Decreases alcohol-withdrawal-related anxiety. Decreased blood pressure and increased brain blood flow. Helps to increase lymph flow to the stomach and decrease stomach ulcers. Stabilizes blood enkephalins - natural peptides that can reduce stress.

Mechanism of action

Selank peptide is known that the classical benzodiazepines act via gamma-aminobutyric acid (GABA) type A receptors. They enhance the GABA effect by allosteric modulation, which increases the frequency of opening of channels for chlorine ions. The Selank action mechanism may be related to its ability to affect the performance of the GABAergic system.

Side effects

These are the possible side effects:
Anxiety
Headaches
Nausea
Dizziness
Fatigue

Description

SELANK Synthetic is a single, non-glycosylated polypeptide chain containing 7 amino acids, having a molecular mass of 751.89 Dalton and a Molecular formula of C₃₃H₅₇N₁₁O_9.

Selank peptide Preparation Products And Raw materials

Raw materials

Preparation Products

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Selank peptide Suppliers

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View Lastest Price from Selank peptide manufacturers

Ningbo Qingteng Plastic Cost.,Ltd.

Product: Selank 5mg 10mg 30mg 129954-34-3
Price: US $10.00/box
Min. Order: 1box
Purity: 99.99%
Supply Ability: 9999
Release date: 2025-12-08

Biochem Technology Limited

Product: selank 129954-34-3
Price: US $0.00/g
Min. Order: 10g
Purity: 99.99%HPLC
Supply Ability: 1000g
Release date: 2025-11-06

Ningbo Qingteng Plastic Cost.,Ltd.

Product: Selank peptide
Price: US $20.00/box
Min. Order: 1box
Purity: 99
Supply Ability: in stock
Release date: 2025-10-13

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