GET-73

Product Name: GET-73
CAS No.: 202402-01-5
Chemical Name: GET-73
Synonyms: GET-73;GET 73;GET-73;GET73;GET73, 10 mM in DMSO;Gamma hydroxybutyric acid analogue;4-Methoxy-N-(4-(trifluoromethyl)benzyl)butanamide;4-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]butanamide;Butanamide, 4-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]-;neuroprotective,anti-alcohol,inhibit,γ-hydroxybutyric acid,mGluR5,GHB,Inhibitor,GET73,GET-73,anxiolytic,glutamate
CBNumber: CB33162603
Molecular Formula: C13H16F3NO2
Formula Weight: 275.27
MOL File: 202402-01-5.mol

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GET-73 Property

Boiling point:: 394.7±42.0 °C(Predicted)
Density: 1.175±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO : 100 mg/mL (363.28 mM; Need ultrasonic)
pka: 15.11±0.46(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: 3877BB
Product name: 4-Methoxy-N-((4-(trifluoromethyl)phenyl)methyl)-butanamide
Packaging: 5mg
Price: $135
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573472
Product name: Get73
Purity: >98%
Packaging: 100mg
Price: $765
Updated: 2021/12/16

Apolloscientific

Product number: BISN0047
Product name: GET-73
Purity: 99%
Packaging: 1mg
Price: $856
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573472
Product name: Get73
Purity: >98%
Packaging: 250mg
Price: $1356.6
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573472
Product name: Get73
Purity: >98%
Packaging: 1g
Price: $2541.5
Updated: 2021/12/16

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GET-73 Chemical Properties,Usage,Production

Uses

GET73 is a γ-hydroxybutyric acid (GHB) analog, a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties. GET73 significantly affects glutamate transmission in the hippocampus[1][2][3].

in vivo

GET73 (5-50 mg/kg; i.g.) exerts an anxiolytic effect in Sprague-Dawley rats exposed to the elevated plus maze (EPM) test^[3].

Animal Model:	Male SD rats (200-300?g and 300–350?g)^[3]
Dosage:	5 mg/kg, 10 mg/kg, 25 mg/kg, 50 mg/kg
Administration:	Oral gavage
Result:	Exerted an anxiolytic effect in rats exposed to the elevated plus maze (EPM) test.

References

[1] Tomasini MC, et al. GET73 Prevents Ethanol-Induced Neurotoxicity in Primary Cultures of Rat Hippocampal Neurons. Alcohol Alcohol. 2016 Mar;51(2):128-35. DOI:10.1093/alcalc/agv094
[2] Ferraro L, et al. GET73 modulates rat hippocampal glutamate transmission: evidence for a functional interaction with mGluR5. Pharmacol Rep. 2011;63(6):1359-71. DOI:10.1016/s1734-1140(11)70700-9
[3] Loche A, et al. Anti-Alcohol and Anxiolytic Properties of a New Chemical Entity, GET73. Front Psychiatry. 2012 Feb 14;3:8. DOI:10.3389/fpsyt.2012.00008

GET-73 Preparation Products And Raw materials

Raw materials

Preparation Products

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GET-73 Suppliers

China 30 India 1 United States 4 Global 35

Shanghai JiYi Biotechnology Co. Ltd.

Tel: 13621943973
Fax: -
Email: sales@shjiyipharmatech.com
Country: China
ProdList: 1166
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71829
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9342
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32222
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

Jingmo (Xiamen) Biotechnology Co., Ltd

Tel: 13621943973; 13621943973
Email: sales@jamxmpharmatech.com
Country: China
ProdList: 1131
Advantage: 58

Shanghai Botuo Biotechnology Co., LTD

Tel: 16621358918
Fax: QQ:402135374
Email: botuopharma888@163.com
Country: China
ProdList: 9208
Advantage: 58

Qingfeng Chem

Tel: 18672943286
Email: brian_zhao@whqfchem.com
Country: China
ProdList: 453
Advantage: 58

202402-01-5, GET-73Related Search:

GET-73

GET 73;GET-73;GET73

Gamma hydroxybutyric acid analogue

4-Methoxy-N-(4-(trifluoromethyl)benzyl)butanamide

neuroprotective,anti-alcohol,inhibit,γ-hydroxybutyric acid,mGluR5,GHB,Inhibitor,GET73,GET-73,anxiolytic,glutamate

Butanamide, 4-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]-

4-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]butanamide

GET73, 10 mM in DMSO

202402-01-5