ChemicalBook > CAS DataBase List > 5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

Product Name
5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
CAS No.
26166-92-7
Chemical Name
5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Synonyms
135586;Thalidomide-5-Br;5-bromo-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione;5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;5-Bromo-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione;1H-Isoindole-1,3(2H)-dione, 5-bromo-2-(2,6-dioxo-3-piperidinyl)-;5-bromo-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione - [B86000];5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione(WXC07613);5-bromo-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1 H-isoindole-1,3-dione
CBNumber
CB33166368
Molecular Formula
C13H9BrN2O4
Formula Weight
337.13
MOL File
26166-92-7.mol
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5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Property

Melting point:
>230 °C
Boiling point:
564.3±45.0 °C(Predicted)
Density 
1.794±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
10.60±0.40(Predicted)
form 
Solid
color 
Off-white to gray
InChI
InChI=1S/C13H9BrN2O4/c14-6-1-2-7-8(5-6)13(20)16(12(7)19)9-3-4-10(17)15-11(9)18/h1-2,5,9H,3-4H2,(H,15,17,18)
InChIKey
MWMSBQXTHIEBNT-UHFFFAOYSA-N
SMILES
C1(=O)C2=C(C=C(Br)C=C2)C(=O)N1C1CCC(=O)NC1=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B6550
Product name
5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Packaging
1G
Price
$90
Updated
2026/03/19
TCI Chemical
Product number
B6550
Product name
5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Packaging
5G
Price
$270
Updated
2026/03/19
Acrotein
Product number
H-7895
Product name
5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Purity
97%
Packaging
10g
Price
$623.33
Updated
2021/12/16
Abosyn
Product number
10-3245
Product name
5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Purity
95%-98%
Packaging
1g
Price
$1199
Updated
2021/12/16
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5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Chemical Properties,Usage,Production

Description

5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a derivative of thalidomide with an bromide atom on the benzyl ring

Chemical Properties

White to Light gray to Light yellow powder to crystal

Uses

Thalidomide-5-Br (compound 4) is a compound with a bromodomain. Thalidomide-5-Br can be used in the research of inflammation, tumor and neurology[1].

References

[1] Yeung, et al. "Novel thalidomide analogues with potent NFκB and TNF expression inhibition." MedChemComm 2.11 (2011): 1073-1078.

5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Suppliers

Baimei Jihua (Henan) Pharmaceutical Technology Co., Ltd
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037188900765 18037465274
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QQ3430974218
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enyawanglei@sina.cn
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China
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14050
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Jilin Province Woda Biotechnology Co., Ltd.
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13504435624
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1927928688@qq.com
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China
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58
SuZhou Medinoah Co.,LTD.
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0512-69561983 13914027025
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0512-69561982
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zhang_q@medinoah.com
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China
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3886
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Amatek Scientific Co. Ltd.
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0512-56316828
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0512-56316826
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info@amateksci.com
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China
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PharmaBlock Sciences (Nanjing),Inc.
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025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
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China
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5000
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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sales8178@energy-chemical.com
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China
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Daicel Chiral Technologies (China)CO.,LTD
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021-50460086-9 15921403865
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+86-21-50462321
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han_yajun@dctc.daicel.com
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China
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Shanghai Topbiochem Technology Co., Ltd
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021-58170097 15801866362;
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info@topbiochem.com
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China
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Bide Pharmatech Ltd.
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400-400-164-7117 18317119277
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+86-21-61629029
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product02@bidepharm.com
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China
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40000
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HangZhou YuHao Chemical Technology Co., Ltd.
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0571-82693216
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0571-82880190
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info@yuhaochemical.com
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China
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2028
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View Lastest Price from 5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 26166-92-7
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-26

26166-92-7, 5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneRelated Search:


  • 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
  • 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione(WXC07613)
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  • 1H-Isoindole-1,3(2H)-dione, 5-bromo-2-(2,6-dioxo-3-piperidinyl)-
  • 5-bromo-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1 H-isoindole-1,3-dione
  • 5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
  • 5 bromo 2 (2,6 dioxopiperidin 3 yl)isoindole 1,3 dione,5bromo2(2,6dioxopiperidin3yl)isoindole1,3dione
  • 5-bromo-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione
  • Thalidomide-5-Br
  • 5-bromo-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione - [B86000]
  • 5-Bromo-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
  • 26166-92-7
  • 6166-92-7