ChemicalBook > CAS DataBase List > LTI-291

LTI-291

Product Name
LTI-291
CAS No.
1919820-28-2
Chemical Name
LTI-291
Synonyms
184658;TI-291;LTI-291;CS-2568;LTI291;LTI 291;Gcase activator 1, 10 mM in DMSO;Inhibitor,Gcase activator1,inhibit,Gcase activator-1,Glucosidase,Gcase activator 1;5,7-dimethyl-N-(trans-4-(pentyloxy)cyclohexyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5,7-dimethyl-N-((1r,4r)-4-(pentyloxy)cyclohexyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 5,7-dimethyl-N-[trans-4-(pentyloxy)cyclohexyl]-
CBNumber
CB33167325
Molecular Formula
C20H30N4O2
Formula Weight
358.48
MOL File
1919820-28-2.mol
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LTI-291 Property

Density 
1.21±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
form 
A solid
pka
11.03±0.40(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
L473535
Product name
LTI-291
Packaging
5mg
Price
$420
Updated
2021/12/16
ChemScene
Product number
CS-0026754
Product name
Gcaseactivator1
Purity
98.77%
Packaging
25mg
Price
$588
Updated
2021/12/16
ChemScene
Product number
CS-0026754
Product name
Gcaseactivator1
Purity
98.77%
Packaging
50mg
Price
$948
Updated
2021/12/16
ChemScene
Product number
CS-0026754
Product name
Gcaseactivator1
Purity
98.77%
Packaging
100mg
Price
$1440
Updated
2021/12/16
ChemScene
Product number
CS-0026754
Product name
Gcaseactivator1
Purity
98.77%
Packaging
5mg
Price
$168
Updated
2021/12/16
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LTI-291 Chemical Properties,Usage,Production

Uses

Gcase activator 1 is an activator of glucocerebrosidase (Gcase), with activation rates of more than 60% (1 μM) and between 10%-20% (0.1 μM). Gcase activator 1 can be used for Parkinson's disease and endometriosis research[1].

References

[1] Renato T. Skerlj, et al. Methods of treatment and combination therapies using gcase activator heterobicyclic and related compounds. WO 2017192841 A1.

LTI-291 Preparation Products And Raw materials

Raw materials

Preparation Products

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LTI-291 Suppliers

China 60 India 1 United States 8 Global 69
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View Lastest Price from LTI-291 manufacturers

Career Henan Chemical Co
Product
LTI-291 1919820-28-2
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2019-12-25

1919820-28-2, LTI-291Related Search:


  • LTI-291
  • 5,7-dimethyl-N-((1r,4r)-4-(pentyloxy)cyclohexyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
  • 184658
  • LTI291;LTI 291
  • CS-2568
  • TI-291
  • Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 5,7-dimethyl-N-[trans-4-(pentyloxy)cyclohexyl]-
  • 5,7-dimethyl-N-(trans-4-(pentyloxy)cyclohexyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
  • Inhibitor,Gcase activator1,inhibit,Gcase activator-1,Glucosidase,Gcase activator 1
  • Gcase activator 1, 10 mM in DMSO
  • 1919820-28-2