Memogain

Product Name: Memogain
CAS No.: 224169-27-1
Chemical Name: Memogain
Synonyms: GLN-1062;Memogain;GLN-1062 ，E2227;GLN-1062, 10 mM in DMSO;Benzgalantamine (GLN-1062);Inhibitor,GLN-1062,GLN 1062,inhibit,GLN1062;(4aS,6R,8aS)-3-Methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-yl benzoate;Galantamine benzoate D6Q: What is Galantamine benzoate D6 Q: What is the CAS Number of Galantamine benzoate D6;6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, 6-benzoate, (4aS,6R,8aS)-;Galantamine benzoateQ: What is Galantamine benzoate Q: What is the CAS Number of Galantamine benzoate Q: What is the storage condition of Galantamine benzoate
CBNumber: CB33175551
Molecular Formula: C24H25NO4
Formula Weight: 391.46
MOL File: 224169-27-1.mol

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Memogain Property

Boiling point:: 523.2±50.0 °C(Predicted)
Density: 1.28±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 7.78±0.40(Predicted)
form: Solid
color: White to yellow
InChI: InChI=1S/C24H25NO4/c1-25-13-12-24-11-10-18(28-23(26)16-6-4-3-5-7-16)14-20(24)29-22-19(27-2)9-8-17(15-25)21(22)24/h3-11,18,20H,12-15H2,1-2H3/t18-,20-,24-/m0/s1
InChIKey: JKVNJTYHRABHIY-WXVUKLJWSA-N
SMILES: N1(C)CC2=CC=C(OC)C3O[C@]4([H])[C@@](C=C[C@H](OC(=O)C5=CC=CC=C5)C4)(C2=3)CC1

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Hazard and Precautionary Statements (GHS)

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Memogain Chemical Properties,Usage,Production

Uses

Galantamine Benzoate-D3 is an isotopic labelled compound of Galantamine Benzoate, a pro-drug that slows down plaque deposition and ameliorates behavior in 5X familial Alzheimer's disease mice.

in vivo

Benzgalantamine (Memogain, 0.3-3 mg/kg, intranasal, twice a day for 2 weeks) improves cognitive function by promoting neurogenesis in the hippocampus, specifically in the dentate gyrus and CA1 regions of the hippocampus in rats models^[2].

Animal Model:	Sprague Dawley rats models^[2]
Dosage:	0.3-3 mg/kg
Administration:	intranasal, twice a day for 2 weeks
Result:	Increased the number of newly generated cells and immunolabeling of synaptic markers in the dentate gyrus and CA1 regions of the hippocampus.

Memogain Preparation Products And Raw materials

Raw materials

Preparation Products

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Memogain Suppliers

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224169-27-1, MemogainRelated Search:

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Memogain

GLN-1062

6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, 6-benzoate, (4aS,6R,8aS)-

Galantamine benzoate D6Q: What is Galantamine benzoate D6 Q: What is the CAS Number of Galantamine benzoate D6

Galantamine benzoateQ: What is Galantamine benzoate Q: What is the CAS Number of Galantamine benzoate Q: What is the storage condition of Galantamine benzoate

Inhibitor,GLN-1062,GLN 1062,inhibit,GLN1062

(4aS,6R,8aS)-3-Methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-yl benzoate

GLN-1062, 10 mM in DMSO

Benzgalantamine (GLN-1062)

GLN-1062 ，E2227

224169-27-1