NVX-207

Product Name: NVX-207
CAS No.: 745020-66-0
Chemical Name: NVX-207
Synonyms: NVX-207;NVX 207,NVX207;Lup-20(29)-en-28-oic acid, 3-(acetyloxy)-, 2-amino-3-hydroxy-2-(hydroxymethyl)propyl ester, (3β)-
CBNumber: CB33175566
Molecular Formula: C36H59NO6
Formula Weight: 601.87
MOL File: 745020-66-0.mol

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NVX-207 Property

Boiling point:: 664.8±55.0 °C(Predicted)
Density: 1.14±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 125 mg/mL (207.69 mM)
pka: 11.71±0.20(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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NVX-207 Chemical Properties,Usage,Production

Uses

NVX-207, a Betulinic acid-derived anti-cancer compound, shows anti-tumor activity (mean IC50=3.5 μM) against various human and canine cell lines. NVX-207-induced apoptosis is associated with activation of the intrinsic apoptotic pathway via cleavage of caspases -9, -3, -7 and of PARP[1].

in vivo

Intravenous application of NVX-207 in mice is well tolerated^[1].

References

[1] Willmann M, et al. Characterization of NVX-207, a novel betulinic acid-derived anti-cancer compound. Eur J Clin Invest. 2009;39(5):384-394. DOI:10.1111/j.1365-2362.2009.02105.x
[2] Bache M, et al. Betulinic acid derivatives NVX-207 and B10 for treatment of glioblastoma--an in vitro study of cytotoxicity and radiosensitization. Int J Mol Sci. 2014 Oct 30;15(11):19777-90. DOI:10.3390/ijms151119777

NVX-207 Preparation Products And Raw materials

Raw materials

Preparation Products

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NVX-207 Suppliers

China 11 United States 3 Global 14

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Kaifeng Mingren Pharmaceutical Co.,LTD

Tel: 0371-65741762
Fax: QQ：2860768577
Email: sales@hasunny.com
Country: China
ProdList: 2380
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
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Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
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Adooq Bioscience LLC

Tel: 400-025-6535
Email: sales@adooq.cn
Country: China
ProdList: 6215
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Guangzhou Kati Biotechnology Co., Ltd.

Tel: 13128698830
Country: CHINA
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Jinan Lemon Biotechnology Co., Ltd.

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Country: China
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Guangzhou Baide Biotechnology Co., Ltd.

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Guangzhou Junuo Biotechnology Co., Ltd.

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Shanghai Hao Zhun Biological Technology Co., Ltd.

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Email: info@zzsrm.com
Country: CHINA
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745020-66-0, NVX-207Related Search:

NVX-207

Lup-20(29)-en-28-oic acid, 3-(acetyloxy)-, 2-amino-3-hydroxy-2-(hydroxymethyl)propyl ester, (3β)-

NVX 207,NVX207

745020-66-0