5-Hydroxy-2-nitrobenzaldehyde
- Product Name
- 5-Hydroxy-2-nitrobenzaldehyde
- CAS No.
- 42454-06-8
- Chemical Name
- 5-Hydroxy-2-nitrobenzaldehyde
- Synonyms
- 3-Formyl-4-nitrophenol;LABOTEST-BB LT00233113;5-Hydroxy-2-nitrobenzaL;2-NITRO-5-HYDROXYBENZALDE;5-Hydroxy-2-nitrobenzaldehy;3-HYDROXY-6-NITROBENZALDEHYDE;5-HYDROXY-2-NITROBENZALDEHYDE;6-NITRO-3-HYDROXY BENZALDHYDE;6-NITRO-3-HYDROXYBENZALDEHYDE;2-NITRO-5-HYDROXYBENZALDEHYDE
- CBNumber
- CB3318890
- Molecular Formula
- C7H5NO4
- Formula Weight
- 167.12
- MOL File
- 42454-06-8.mol
5-Hydroxy-2-nitrobenzaldehyde Property
- Melting point:
- 165-169 °C (lit.)
- Boiling point:
- 373.0±32.0 °C(Predicted)
- Density
- 1.500±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in methanol.
- pka
- 6.34±0.10(Predicted)
- form
- Solid
- color
- Pale Yellow to Yellow
- Sensitive
- Air Sensitive
- BRN
- 1910196
- Stability:
- Air Sensitive
- CAS DataBase Reference
- 42454-06-8(CAS DataBase Reference)
- NIST Chemistry Reference
- 5-Hydroxy-2-nitro-benzaldehyde(42454-06-8)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H48107
- Product name
- 5-Hydroxy-2-nitrobenzaldehyde
- Purity
- 98%
- Packaging
- 5g
- Price
- $108.3
- Updated
- 2025/07/31
- Product number
- H48107
- Product name
- 5-Hydroxy-2-nitrobenzaldehyde
- Purity
- 98%
- Packaging
- 25g
- Price
- $149.15
- Updated
- 2025/07/31
- Product number
- H1039
- Product name
- 5-Hydroxy-2-nitrobenzaldehyde
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $113
- Updated
- 2025/07/31
- Product number
- H1039
- Product name
- 5-Hydroxy-2-nitrobenzaldehyde
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $352
- Updated
- 2025/07/31
- Product number
- H941005
- Product name
- 5-Hydroxy-2-nitrobenzaldehyde
- Packaging
- 10g
- Price
- $130
- Updated
- 2021/12/16
5-Hydroxy-2-nitrobenzaldehyde Chemical Properties,Usage,Production
Chemical Properties
Yellow powder
Uses
5-Hydroxy-2-nitrobenzaldehyde is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.
Synthesis Reference(s)
The Journal of Organic Chemistry, 44, p. 409, 1979 DOI: 10.1021/jo01317a021
Synthesis
100-83-4
42454-06-8
The general procedure for the synthesis of 5-hydroxy-2-nitrobenzaldehyde (formula VI) using m-hydroxybenzaldehyde (formula V, R5=H) as starting material was as follows: 3 g of m-hydroxybenzaldehyde was slowly added to 30 ml of nitric acid (density = 1.17, 28% solution), and the temperature of the solution was maintained at a temperature between 35°C and 45°C during the reaction. After the addition was completed, hydrolysis was carried out and the reaction mixture was subsequently left to stand at room temperature. The reaction produced a yellow precipitate which was filtered and the precipitate was refluxed in 20 ml of benzene for 15 to 20 minutes. The insoluble material was separated and purified by recrystallization in water. 5-Hydroxy-2-nitrobenzaldehyde (formula VI) was finally obtained in 25% yield with a melting point of 167°C (molecular formula: C7H5NO4, molecular weight = 167).
References
[1] Helvetica Chimica Acta, 1992, vol. 75, # 4, p. 1185 - 1197
[2] Patent: US5139707, 1992, A
[3] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 3, p. 444 - 452
[4] Journal of the Chemical Society, 1925, vol. 127, p. 2171
[5] Journal of the Chemical Society, 1925, vol. 127, p. 876,877
5-Hydroxy-2-nitrobenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Hydroxy-2-nitrobenzaldehyde manufacturers
- Product
- 5-Hydroxy-2-nitrobenzaldehyde 42454-06-8
- Price
- US $1.50/g
- Min. Order
- 1g
- Purity
- 99.0% Min
- Supply Ability
- 100 Tons
- Release date
- 2025-09-25
- Product
- 5-Hydroxy-2-nitrobenzaldehyde 42454-06-8
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-12
- Product
- 5-Hydroxy-2-nitrobenzaldehyde 42454-06-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-15