2,5-Pyrrolidinedione, 1-[(5-azido-1-oxopentyl)oxy]-

Product Name: 2,5-Pyrrolidinedione, 1-[(5-azido-1-oxopentyl)oxy]-
CAS No.: 478801-48-8
Chemical Name: 2,5-Pyrrolidinedione, 1-[(5-azido-1-oxopentyl)oxy]-
Synonyms: N3-C4-NHS ester;2,5-dioxopyrrolidin-1-yl 5-azidopentanoate;5-Azidopentanoic acid N-hydroxysuccinimide ester;5-azidopentanoic acid N-hydroxysuccinimidyl ester;2,5-Pyrrolidinedione, 1-[(5-azido-1-oxopentyl)oxy]-;5-Azidopentanoic acid N-hydroxysuccinimide ester - [A1981];Inhibitor,N3 C4 NHS ester,inhibit,N-3-C4-NHS ester,N3C4NHS ester,ADC Linkers,Antibody-drug conjugates linkers
CBNumber: CB33231484
Molecular Formula: C9H12N4O4
Formula Weight: 240.21598
MOL File: 478801-48-8.mol

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2,5-Pyrrolidinedione, 1-[(5-azido-1-oxopentyl)oxy]- Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Synthonix

Product number: A1981
Product name: 5-AzidopentanoicacidN-hydroxysuccinimideester
Purity: 96%
Packaging: 250mg
Price: $80
Updated: 2021/12/16

Synthonix

Product number: A1981
Product name: 5-AzidopentanoicacidN-hydroxysuccinimideester
Purity: 96%
Packaging: 500mg
Price: $130
Updated: 2021/12/16

Synthonix

Product number: A1981
Product name: 5-AzidopentanoicacidN-hydroxysuccinimideester
Purity: 96%
Packaging: 1g
Price: $220
Updated: 2021/12/16

ChemScene

Product number: CS-0105080
Product name: N3-C4-NHSester
Packaging: 100mg
Price: $460
Updated: 2021/12/16

Matrix Scientific

Product number: 186505
Product name: 5-Azidopentanoic acid N-hydroxysuccinimide ester
Purity: 95.00
Packaging: 1g
Price: $990
Updated: 2021/12/16

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2,5-Pyrrolidinedione, 1-[(5-azido-1-oxopentyl)oxy]- Chemical Properties,Usage,Production

Uses

N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

Non-cleavable Linker

References

[1] Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers. J Med Chem. 2017 Dec 14;60(23):9490-9507. DOI:10.1021/acs.jmedchem.7b00736

2,5-Pyrrolidinedione, 1-[(5-azido-1-oxopentyl)oxy]- Preparation Products And Raw materials

Raw materials

Preparation Products

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2,5-Pyrrolidinedione, 1-[(5-azido-1-oxopentyl)oxy]- Suppliers

China 31 United States 4 Global 35

Mashilabs (Shanghai) Co.,Ltd.

Tel: 19916721580
Fax: QQ：3154870176
Email: mafarm@126.com
Country: China
ProdList: 4539
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80534353 19917294565
Email: et@chemextension.com
Country: China
ProdList: 3840
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
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Email: info@efebio.com
Country: China
ProdList: 9803
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

SuZhou Medinoah Co.,LTD.

Tel: 0512-69561983 13914027025
Fax: 0512-69561982
Email: zhang_q@medinoah.com
Country: China
ProdList: 3893
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Henan Alpha Chemical Co., Ltd.

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Country: China
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Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 20405
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
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Shanxi Xuanran Import and Export Trade Co., Ltd.

Tel: +8617735180244
Email: mike_yan@xuanranglobal.com
Country: CHINA
ProdList: 4017
Advantage: 58

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View Lastest Price from 2,5-Pyrrolidinedione, 1-[(5-azido-1-oxopentyl)oxy]- manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: N3-C4-NHS ester 478801-48-8
Price: US $0.00/mg
Min. Order: 250mg
Purity: >95.00%
Supply Ability: 250mg
Release date: 2024-05-11

478801-48-8, 2,5-Pyrrolidinedione, 1-[(5-azido-1-oxopentyl)oxy]-Related Search:

2,5-Pyrrolidinedione, 1-[(5-azido-1-oxopentyl)oxy]-

5-Azidopentanoic acid N-hydroxysuccinimide ester

2,5-dioxopyrrolidin-1-yl 5-azidopentanoate

5-azidopentanoic acid N-hydroxysuccinimidyl ester

N3-C4-NHS ester

Inhibitor,N3 C4 NHS ester,inhibit,N-3-C4-NHS ester,N3C4NHS ester,ADC Linkers,Antibody-drug conjugates linkers

5-Azidopentanoic acid N-hydroxysuccinimide ester - [A1981]

478801-48-8