4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE
- Product Name
- 4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE
- CAS No.
- 94-19-9
- Chemical Name
- 4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE
- Synonyms
- setd;etazol;etazole;globucid;ethazole;globucin;globuzid;sethadil;aethazol;berlophen
- CBNumber
- CB3325377
- Molecular Formula
- C10H12N4O2S2
- Formula Weight
- 284.36
- MOL File
- 94-19-9.mol
4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Property
- Melting point:
- 185.5-186.0°
- Density
- 1.3410 (rough estimate)
- refractive index
- 1.6440 (estimate)
- pka
- pKa 5.36(H2O t = 37) (Uncertain)
- Water Solubility
- 215mg/L(20 ºC)
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- Toxicity
- LD50 intraperitoneal in mouse: 1459mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 008104
- Product name
- 4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide
- Packaging
- 1g
- Price
- $305
- Updated
- 2021/12/16
- Product number
- 3860AF
- Product name
- 4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide
- Packaging
- 1g
- Price
- $461
- Updated
- 2021/12/16
- Product number
- CHM0165391
- Product name
- 4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE
- Purity
- 98.00%
- Packaging
- 500MG
- Price
- $762.3
- Updated
- 2021/12/16
- Product number
- BBC/507
- Product name
- 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
- Packaging
- 10g
- Price
- $501
- Updated
- 2021/12/16
- Product number
- BBC/507
- Product name
- 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
- Packaging
- 5g
- Price
- $371
- Updated
- 2021/12/16
4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Chemical Properties,Usage,Production
Originator
Sul-Spansion,SKF,US,1956
Definition
ChEBI: 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide is a member of benzenes and a sulfonamide.
Manufacturing Process
0.163 mol of 2-amino-5-ethyl-1,3,4-thiadiazole was covered with 43 parts of anhydrous pyridine. To the mixture was added 50 parts (0.214 mol) of pacetylaminobenzenesulfonyl chloride with vigorous shaking at 50°C to 60°C. The reaction mixture was then heated to 125°C. When the mixture had cooled somewhat it was placed in a Claisen flask and 27.6 parts (0.69 mol) of sodium hydroxide dissolved in 110 parts of water was added through a dropping funnel while distilling off a mixture of pyridine and water. The distillation was stopped when the temperature reached 100°C and the residual liquor in the flask heated at 95°C for 30 minutes.The reaction mixture was then poured into 1,650 parts of hot water, the pH adjusted to 8 to 9, decolorizing charcoal was added and the whole was heated on the steam for 15 minutes. The charcoal was filtered off and the hot filtrate neutralized and cooled. The 2-(sulfanilamido)-5-ethyl-1,3,4-thiadiazole was purified by repeated crystallization from boiling water.
Therapeutic Function
Antibacterial
4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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