2-VINYL-4-QUINAZOLINOL

Product Name: 2-VINYL-4-QUINAZOLINOL
CAS No.: 91634-12-7
Chemical Name: 2-VINYL-4-QUINAZOLINOL
Synonyms: STIMA 1;2-Vinylquinazolin-4-ol;2-VINYL-4-QUINAZOLINOL;p53 Activator VII, STIMA-1;2-Vinylquinazolin-4(3H)-one;2-VINYL-3H-QUINAZOLIN-4-ONE;2-vinylquinazolin-4(1H)-one;2-Vinyl-4(3H)-quinazolinone;2-ethenyl-1H-quinazolin-4-one;4(3H)-Quinazolinone, 2-ethenyl-
CBNumber: CB3327694
Molecular Formula: C10H8N2O
Formula Weight: 172.18
MOL File: 91634-12-7.mol

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2-VINYL-4-QUINAZOLINOL Property

Melting point:: >200°C (dec.)
Boiling point:: 315.4±25.0 °C(Predicted)
Density: 1.20±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 1.91±0.20(Predicted)
color: White to Off-White
Stability:: Light Sensitive
InChI: 1S/C10H8N2O/c1-2-9-11-8-6-4-3-5-7(8)10(13)12-9/h2-6H,1H2,(H,11,12,13)
InChIKey: VCHFWHQHIKFOIC-UHFFFAOYSA-N
SMILES: n1c2c(c(nc1C=C)O)cccc2

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Safety

Hazard Codes: Xi
WGK Germany: WGK 2
HazardClass: IRRITANT
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 506168-M
Product name: p53 Activator VII, STIMA-1 - CAS 91634-12-7 - Calbiochem
Packaging: 25MG
Price: $135
Updated: 2025/07/31

TRC

Product number: B126350
Product name: 2-Ethenyl-3,4-dihydroquinazolin-4-one
Packaging: 50mg
Price: $100
Updated: 2021/12/16

Matrix Scientific

Product number: 009820
Product name: 2-Vinyl-4-quinazolinol
Purity: 97%
Packaging: 250mg
Price: $100
Updated: 2021/12/16

AK Scientific

Product number: 5436AC
Product name: 2-Vinylquinazolin-4-ol
Packaging: 250mg
Price: $185
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0021994
Product name: 2-VINYL-4-QUINAZOLINOL
Purity: 95.00%
Packaging: 1G
Price: $852.55
Updated: 2021/12/16

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2-VINYL-4-QUINAZOLINOL Chemical Properties,Usage,Production

Uses

STIMA-1 can stimulate mutant p53 DNA binding in vitro and induce expression of p53 target proteins and trigger apoptosis in mutant p53-expressing human tumor cells[1].

References

[1] Nicole Zache, et al. Mutant p53 targeting by the low molecular weight compound STIMA-1. Mol Oncol. 2017 May;11(5):595. DOI:10.1002/1878-0261.12065

2-VINYL-4-QUINAZOLINOL Preparation Products And Raw materials

Raw materials

Preparation Products

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2-VINYL-4-QUINAZOLINOL Suppliers

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91634-12-7, 2-VINYL-4-QUINAZOLINOLRelated Search:

6-BROMO-2-VINYL-4-QUINAZOLINOL 2-[2-(4-METHOXYPHENYL)-VINYL]QUINAZOLIN-4-OL 2-VINYL-4-QUINAZOLINOL 6-Bromo-2-vinyl-4-quinazolinol

2-VINYL-3H-QUINAZOLIN-4-ONE

2-VINYL-4-QUINAZOLINOL

2-Vinylquinazolin-4(3H)-one

STIMA 1

4(3H)-Quinazolinone, 2-ethenyl-

2-vinylquinazolin-4(1H)-one

2-ethenyl-1H-quinazolin-4-one

2-Ethenyl-3,4-dihydroquinazolin-4-one

2-Vinylquinazolin-4-ol

2-Vinylquinazolin-4-ol|||p53 Activator VII

p53 Activator VII, STIMA-1

2-Vinyl-4(3H)-quinazolinone

91634-12-7