CAIX Inhibitor S4

Product Name: CAIX Inhibitor S4
CAS No.: 1330061-67-0
Chemical Name: CAIX Inhibitor S4
Synonyms: S4 >=98% (HPLC);CAIX Inhibitor S4;CAIX Inhibitor S4, 10 mM in DMSO;4-(3-(3,5-Dimethylphenyl)ureido)phenyl sulfamate;4-[[[(3,5-Dimethylphenyl)amino]carbonyl]amino]phenyl sulfamate;Sulfamic acid, 4-[[[(3,5-dimethylphenyl)amino]carbonyl]amino]phenyl ester
CBNumber: CB33309354
Molecular Formula: C15H17N3O4S
Formula Weight: 335.38
MOL File: 1330061-67-0.mol

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CAIX Inhibitor S4 Property

Density: 1.429±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 30 mg/ml
form: A solid
pka: 8.63±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2031
Product name: S4
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $105
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2031
Product name: S4
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $424
Updated: 2024/03/01

TRC

Product number: S019995
Product name: S4
Packaging: 50mg
Price: $470
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0009832
Product name: S-4
Purity: 95.00%
Packaging: 5MG
Price: $455.08
Updated: 2021/12/16

AK Scientific

Product number: 6486DK
Product name: 4-[(3,5-Dimethylphenyl)Ureido]PhenylSulfamate
Packaging: 5mg
Price: $187
Updated: 2021/12/16

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CAIX Inhibitor S4 Chemical Properties,Usage,Production

Uses

S4 is a sulfamate carbonic anhydrase IX (CAIX) inhibitor in colorectal carcinoma cell lines.

Biological Activity

S4 is a potent and selective inhibitor against sulfamate carbonic anhydrase (CA) subtypes CAIX & CAXII (Ki = 2, 7, 546, 5600 nM against human CA XII, IX, II, and I, respectively). S4 selectively inhibits migration upon anoxia/hypoxia-induced CAIX expression in cancer cultures (% inhibition/conc./cell line = 54%/100 μM/WRO, 65%/33 μM/MDA-MB-231), while exhibiting no inhibitory effects under normoxia or among non-CAIX-expressing cells (HCT116 & RT112). Daily intraperitoneal injection (10 mg/kg) is reported to reduce the metastatic tumor burden in lungs of mice bearing orthotopic eGFP-MDA-MB-231 tumors in vivo.

storage

Store at +4°C

CAIX Inhibitor S4 Preparation Products And Raw materials

Raw materials

Preparation Products

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CAIX Inhibitor S4 Suppliers

China 43 United Kingdom 1 United States 5 Global 49

Nantong Hi-Future Biotechnology Co., Ltd

Tel: 18051384581
Email: sales@chemhifuture.com
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
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Email: info@efebio.com
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Shanghai YuanYe Biotechnology Co., Ltd.

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Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
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ShangHai Biochempartner Co.,Ltd

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Shanghai Chaolan Chemical Technology Center

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Shanghai Hongye Biotechnology Co. Ltd

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Email: sales@glpbio.cn
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
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Hangzhou Huarong Pharm Co., Ltd.

Tel: 571-86758373 +8613588754946
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Changzhou Chenhong Biotechnology Co., Ltd.

Tel: 0519-85788828 13775037613
Email: sales@chemrenpharm.com
Country: China
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View Lastest Price from CAIX Inhibitor S4 manufacturers

hebei hongtan Biotechnology Co., Ltd

Product: S4 1330061-67-0
Price: US $30.00/g
Min. Order: 10g
Purity: 98%
Supply Ability: 2000kg
Release date: 2024-05-15

Shanghai Longyu Biotechnology Co., Ltd.

Product: S4 1330061-67-0
Price: US $1.00/g
Min. Order: 1g
Purity: 99
Supply Ability: 20tons
Release date: 2022-01-18

Shanghai Chinqesen Biotechnology Co., Ltd.

Product: CAIX Inhibitor S4 1330061-67-0
Price: US $30.00-10.00/BOX
Min. Order: 10BOX
Purity: 99
Supply Ability: 20TONS
Release date: 2023-11-08

1330061-67-0, CAIX Inhibitor S4Related Search:

4-[[[(3,5-Dimethylphenyl)amino]carbonyl]amino]phenyl sulfamate

CAIX Inhibitor S4

Sulfamic acid, 4-[[[(3,5-dimethylphenyl)amino]carbonyl]amino]phenyl ester

S4 >=98% (HPLC)

4-(3-(3,5-Dimethylphenyl)ureido)phenyl sulfamate

CAIX Inhibitor S4, 10 mM in DMSO

1330061-67-0