(4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE

Product Name: (4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE
CAS No.: 251570-03-3
Chemical Name: (4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE
Synonyms: 4-CHLORO-3-FLUOROBENZYLCYANIDE;3-FLUORO-4-CHLOROBENZYL CYANIDE;3-FLUORO-4-CHLORO PHENYLACETONITRILE;4-CHLORO-3-FLUOROPHHENYLACETONITRILE;4-Chloro-3-fluorobenzeneacetonitrile;Benzeneacetonitrile, 4-chloro-3-fluoro-;(4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE;2-(4-chloro-3-fluorophenyl)acetonitrile;3-Fluoro-4-Chloro Phenylacetonitrile 3-Fluoro-4-Chlorobenzyl Cyanide
CBNumber: CB3331615
Molecular Formula: C8H5ClFN
Formula Weight: 169.58
MOL File: 251570-03-3.mol

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(4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE Property

Boiling point:: 253.4±25.0 °C(Predicted)
Density: 1.286±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Oil
color: Beige to Brown
CAS DataBase Reference: 251570-03-3(CAS DataBase Reference)

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Safety

Hazard Codes: T
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39
RIDADR: 3276
Hazard Note: Toxic
HS Code: 2926907090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: C384670
Product name: 4-Chloro-3-fluorophenylacetonitrile
Packaging: 10g
Price: $330
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3737-7-X2
Product name: 4-Chloro-3-fluorophenylacetonitrile
Packaging: 25g
Price: $381
Updated: 2021/12/16

Matrix Scientific

Product number: 116574
Product name: 4-Chloro-3-fluorophenylacetonitrile
Packaging: 10g
Price: $387
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0021804
Product name: 3-FLUORO-4-CHLOROBENZYL CYANIDE
Purity: 95.00%
Packaging: 5G
Price: $909.56
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0021804
Product name: 3-FLUORO-4-CHLOROBENZYL CYANIDE
Purity: 95.00%
Packaging: 10G
Price: $1334.03
Updated: 2021/12/16

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(4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE Chemical Properties,Usage,Production

Chemical Properties

Pale yellow liquid

Synthesis

151-50-8

206362-80-3

251570-03-3

Step 1: Potassium cyanide (KCN, 1.25 g, 19.2 mmol) was added to a solution of 3-fluoro-4-chlorobenzyl bromide (4-(bromomethyl)-1-chloro-2-fluorobenzene, 3.90 g, 17.5 mmol) in dimethyl sulfoxide (DMSO, 60 mL). A small amount of water (H2O, a few mL) was added to promote the dissolution of potassium cyanide. After 1 h of reaction, the reaction mixture was diluted with water and extracted with ethyl acetate (EtOAc). The organic phases were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated. The crude product was purified by silica gel fast column chromatography (Biotage 40M, eluent ratio 9:1 petroleum ether/ethyl acetate) to give 3-fluoro-4-chlorophenylacetonitrile (2-(4-chloro-3-fluorophenyl)acetonitrile, 1.81 g, yield 61.2%) as a yellow crystalline solid.

References

[1] Patent: WO2008/6040, 2008, A1. Location in patent: Page/Page column 114

(4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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(4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE Suppliers

China 93 Germany 3 India 2 Italy 1 Switzerland 1 United Kingdom 9 United States 13 Global 122

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
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Wuhan Chemwish Technology Co., Ltd

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Email: sales@chemwish.com
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Capot Chemical Co., Ltd

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Beijing Ouhe Technology Co., Ltd

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Fax: +86-10-82967029
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JinYan Chemicals(ShangHai) Co.,Ltd.

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Shanghai Harvest Chemical Industrial Co., Ltd.

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Shanghai Hanhong Scientific Co.,Ltd.

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Email: info@hanhongsci.com
Country: China
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Beijing Eternalchem Co,. Ltd.

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Email: sales@eternalchem.com
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Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
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Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Fax: 021-5649-1756
Email: 2819742715@qq.com
Country: China
ProdList: 4000
Advantage: 55

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View Lastest Price from (4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE manufacturers

Career Henan Chemical Co

Product: (4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE 251570-03-3
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-10

251570-03-3, (4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILERelated Search:

Chlorphenesin 4-Chlorobenzyl cyanide (4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE 2,4-DICHLORO-5-FLUOROPHENYLACETONITRILE 4-CHLORO-2,3,6-TRIFLUOROPHENYLACETONITRILE

3-FLUORO-4-CHLOROBENZYL CYANIDE

3-FLUORO-4-CHLORO PHENYLACETONITRILE

3-Fluoro-4-Chloro Phenylacetonitrile 3-Fluoro-4-Chlorobenzyl Cyanide

4-CHLORO-3-FLUOROPHHENYLACETONITRILE

2-(4-chloro-3-fluorophenyl)acetonitrile

(4-CHLORO-3-FLUORO-PHENYL)-ACETONITRILE

4-CHLORO-3-FLUOROBENZYLCYANIDE

Benzeneacetonitrile, 4-chloro-3-fluoro-

4-Chloro-3-fluorobenzeneacetonitrile

251570-03-3

251570-03-0

C8H5CIFN

Fluorine series

Nitrile