ChemicalBook > CAS DataBase List > Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
- Product Name
- Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
- CAS No.
- 1278405-51-8
- Chemical Name
- Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
- Synonyms
- CHK-IN-1;CHKIN1,CHK IN 1;Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
- CBNumber
- CB33339722
- Molecular Formula
- C18H19ClFN5OS
- Formula Weight
- 407.8927632
- MOL File
- 1278405-51-8.mol
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Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
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Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride Chemical Properties,Usage,Production
Description
CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.
CHK-IN-1 can prevent DNA damage repair mechanism from arresting the cell cycle at the G2/M checkpoint[1].
References
[1]. Novel compounds and therapeutic use thereof for protein kinase inhibition. EP 2477496 A1
Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride Suppliers
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