AA-115 (APG-115)

Product Name: AA-115 (APG-115)
CAS No.: 1818393-16-6
Chemical Name: AA-115 (APG-115)
Synonyms: AA-115;APG-115;Alrizomadlin;AA-115 (APG-115);APG-115 (Alrizomadlin);Alrizomadlin, 10 mM in DMSO;Alrizomadlin/APG-115/AA-115;AA 115， APG 115， Alrizomadlin;4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid;4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid
CBNumber: CB33339843
Molecular Formula: C34H38Cl2FN3O4
Formula Weight: 642.59
MOL File: 1818393-16-6.mol

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AA-115 (APG-115) Property

Boiling point:: 805.8±65.0 °C(Predicted)
Density: 1.42±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
pka: 4.76±0.10(Predicted)
color: White to off-white
InChIKey: YJCZPJQGFSSFOL-MNZPCBJKSA-N
SMILES: C12(C(O)=O)CCC(NC([C@@H]3N(CC)C4([C@]5(C6=C(NC5=O)C=C(Cl)C=C6)[C@H]3C3=CC=CC(Cl)=C3F)CCCCC4)=O)(CC1)CC2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0021621
Product name: APG-115
Purity: 98.16%
Packaging: 1mg
Price: $380
Updated: 2021/12/16

ChemScene

Product number: CS-0021621
Product name: APG-115
Purity: 98.16%
Packaging: 5mg
Price: $850
Updated: 2021/12/16

ChemScene

Product number: CS-0021621
Product name: APG-115
Purity: 98.16%
Packaging: 10mg
Price: $1400
Updated: 2021/12/16

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AA-115 (APG-115) Chemical Properties,Usage,Production

Uses

APG 115 is used in the treatment and prevention of osteoarthritis.

in vivo

Alrizomadlin (Delivered orally; 100 mg/kg; once daily; 10 days) enhances radiation antitumor effect in gastric adenocarcinoma in vivo^[3].

Animal Model:	Four-week-old male BALB/c athymic nude mice with MKN45 cells^[3]
Dosage:	100 mg/kg
Administration:	Deliverer orally; once daily; 10 days
Result:	Decreased xenograft tumor growth.

AA-115 (APG-115) Preparation Products And Raw materials

Raw materials

Preparation Products

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AA-115 (APG-115) Suppliers

China 35 United States 4 Global 39

Taizhou Zhongzhi Biotechnology Co., Ltd

Tel: 13012344321
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Zhengzhou Haode Pharmaceutical Technology Co.,Ltd

Tel: 18037386321
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BOC Sciences

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ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185;
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Country: China
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Shanghai Lollane Biological Technology Co.,Ltd.

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Fax: +86-21-52996696
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Shanghai EFE Biological Technology Co., Ltd.

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Shanghai SuperLan Chemcial Technique Centre

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Fan De(Beijing) Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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HANGZHOU CLAP TECHNOLOGY CO.,LTD

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Fax: 86-571-88216895
Email: sales@hzclap.com
Country: CHINA
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1818393-16-6, AA-115 (APG-115)Related Search:

AA-115 (APG-115)

APG-115

AA-115

Alrizomadlin

Bicyclo[2.2.2]octane-1-carboxylic acid, 4-[[[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-1'',2''-dihydro-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-[3H]indol]-5'-yl]carbonyl]amino]-

4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid

4-{[(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indol]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid

APG-115 (Alrizomadlin)

Alrizomadlin/APG-115/AA-115

Alrizomadlin, 10 mM in DMSO

4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid

AA 115， APG 115， Alrizomadlin

1818393-16-6