T-3364366

Product Name: T-3364366
CAS No.: 1356354-09-0
Chemical Name: T-3364366
Synonyms: T-3364366;T-3364366, 10 mM in DMSO;N-[2-({4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-3H,4H-thieno[3,4-d]pyrimidin-2-yl}sulfanyl)ethyl]acetamide;N-[2-[[3,4-Dihydro-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]thio]ethyl]acetamide;Acetamide, N-[2-[[3,4-dihydro-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]thio]ethyl]-
CBNumber: CB33344775
Molecular Formula: C18H16F3N3O3S2
Formula Weight: 443.46
MOL File: 1356354-09-0.mol

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T-3364366 Property

Density: 1.47±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
pka: 15.66±0.46(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 6106
Product name: T3364366
Purity: ≥98%(HPLC)
Packaging: 10
Price: $168
Updated: 2021/12/16

Tocris

Product number: 6106
Product name: T3364366
Purity: ≥98%(HPLC)
Packaging: 50
Price: $704
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BT167269
Product name: T 3364366 NEW
Packaging: 10mg
Price: $105
Updated: 2021/12/16

AK Scientific

Product number: 6511EA
Product name: N-[2-[4-Oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]sulfanylethyl]acetamide
Packaging: 10mg
Price: $191
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BT167269
Product name: T 3364366 NEW
Packaging: 50mg
Price: $367.5
Updated: 2021/12/16

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T-3364366 Chemical Properties,Usage,Production

Uses

T-3364366 is a reversible, slow-binding, thienopyrimidinone delta-5 desaturase (D5D) inhibitor with IC50s of 1.9 nM and 2.1 nM in HepG2 and RLN-10 cells, respectively. T-3364366 exhibits potent D5D (IC500=19 nM) inhibitory activity and excellent selectivity away from delta-6 desaturase (D6D, IC50=6200 nM) and delta-9 desaturase (stearoyl-CoA desaturase, SCD,50 >10000 nM) in the enzymatic activity assay[1].

storage

Store at +4°C

References

[1] Ikuo Miyahisa, et al. T-3364366 Targets the Desaturase Domain of Delta-5 Desaturase with Nanomolar Potency and a Multihour Residence Time. ACS Med Chem Lett. 2016 Aug 10;7(9):868-72. DOI:10.1021/acsmedchemlett.6b00241

T-3364366 Preparation Products And Raw materials

Raw materials

Preparation Products

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T-3364366 Suppliers

China 15 United Kingdom 1 United States 4 Global 20

Nanjing Dulai Biotechnology Co., Ltd.

Tel: 025-846993838003-8003 18013301590
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Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
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Shanghai Hongye Biotechnology Co. Ltd

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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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ShangHai ChuanQian Chemcial Technique Centre

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TargetMol Chemicals Inc.

Tel: 4008200310
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Suzhou Zhixin Biotechnology Co., Ltd.

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Shanghai Yifei Biotechnology Co. , Ltd.

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Shanghai Aladdin Biochemical Technology Co.,Ltd.

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R&D Systems, Inc

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1356354-09-0, T-3364366Related Search:

T-3364366

N-[2-[[3,4-Dihydro-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]thio]ethyl]acetamide

N-[2-({4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-3H,4H-thieno[3,4-d]pyrimidin-2-yl}sulfanyl)ethyl]acetamide

Acetamide, N-[2-[[3,4-dihydro-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]thio]ethyl]-

T-3364366, 10 mM in DMSO

1356354-09-0