CFI-400936

Product Name: CFI-400936
CAS No.: 1338793-07-9
Chemical Name: CFI-400936
Synonyms: CFI-400936;2-(dimethylamino)-2-(2-ethylphenyl)-N-[3-(3-sulfamoylphenyl)-1H-indazol-5-yl]acetamide;Benzeneacetamide, N-[3-[3-(aminosulfonyl)phenyl]-1H-indazol-5-yl]-α-(dimethylamino)-2-ethyl-
CBNumber: CB33345565
Molecular Formula: C25H27N5O3S
Formula Weight: 477.58
MOL File: 1338793-07-9.mol

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CFI-400936 Property

Density: 1.337±0.06 g/cm3(Predicted)
pka: 9.82±0.60(Predicted)

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Hazard and Precautionary Statements (GHS)

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CFI-400936 Chemical Properties,Usage,Production

Description

CFI-400936 is a potent and selective TTK inhibitor with potential anticancer activity. This potent inhibitor of TTK (IC50=3.6nM) demonstrated good activity in cell based assay and selectivity against a panel of human kinases.

Uses

CFI-400936 is a potent TTK inhibitor with an IC50 of 3.6 nM. CFI-400936 has antitumor activity[1].

References

[1] Laufer R, et al. Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides. Bioorg Med Chem. 2014 Sep 1;22(17):4968-97. DOI:10.1016/j.bmc.2014.06.027

CFI-400936 Preparation Products And Raw materials

Raw materials

Preparation Products

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CFI-400936 Suppliers

China 1 United States 2 Global 3

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
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TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
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TargetMol Chemicals Inc.

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Email: marketing@targetmol.com
Country: United States
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1338793-07-9, CFI-400936Related Search:

CFI-400936

2-(dimethylamino)-2-(2-ethylphenyl)-N-[3-(3-sulfamoylphenyl)-1H-indazol-5-yl]acetamide

Benzeneacetamide, N-[3-[3-(aminosulfonyl)phenyl]-1H-indazol-5-yl]-α-(dimethylamino)-2-ethyl-

1338793-07-9