ChemicalBook > CAS DataBase List > 5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile

5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile

Product Name
5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
CAS No.
1350653-26-7
Chemical Name
5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
Synonyms
5-Fluoro-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-3-carbonitrile;5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile;5-fluoro-1- (2-fluorobenzyl)- 1H1pyrazolo[3,4-b]pyridine-3- carbonitrile;5-fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile;1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 5-fluoro-1-[(2-fluorophenyl)methyl]-
CBNumber
CB33353362
Molecular Formula
C14H8F2N4
Formula Weight
270.24
MOL File
1350653-26-7.mol
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5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile Property

Boiling point:
259℃ at 101.3kPa
Density 
1.428 at 20℃
vapor pressure 
0.008Pa at 20℃
storage temp. 
Store at room temperature
pka
-1.24±0.30(Predicted)
Appearance
Off-white to light yellow Solid
InChI
InChI=1S/C14H8F2N4/c15-10-5-11-13(6-17)19-20(14(11)18-7-10)8-9-3-1-2-4-12(9)16/h1-5,7H,8H2
InChIKey
GPEUANAWZCBBHU-UHFFFAOYSA-N
SMILES
C12N(CC3=CC=CC=C3F)N=C(C#N)C1=CC(F)=CN=2
LogP
3.28 at 20℃ and pH6
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Ambeed
Product number
A286628
Product name
5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
Purity
98%
Packaging
100mg
Price
$15
Updated
2021/12/16
Ambeed
Product number
A286628
Product name
5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
Purity
98%
Packaging
250mg
Price
$20
Updated
2021/12/16
Ambeed
Product number
A286628
Product name
5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
Purity
98%
Packaging
1g
Price
$48
Updated
2021/12/16
Ambeed
Product number
A286628
Product name
5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
Purity
98%
Packaging
5g
Price
$155
Updated
2021/12/16
Alichem
Product number
1350653267
Product name
5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
Packaging
250mg
Price
$556.5
Updated
2021/12/16
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5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile Chemical Properties,Usage,Production

Uses

5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile is used as an intermediate for Vericiguat, a drug used to treat heart failure with reduced ejection fraction (HFrEF).

5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile Suppliers

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View Lastest Price from 5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile 1350653-26-7
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-18
Shaanxi Dideu New Materials Co. Ltd
Product
5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile 1350653-26-7
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-06-07
Zison Pharmaceutical (Shandong) Co., Ltd.
Product
5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile 1350653-26-7
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100kgs
Release date
2024-12-18

1350653-26-7, 5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrileRelated Search:

1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 5-fluoro-1-[(2-fluorophenyl)methyl]- 2-[5-Fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(2-phenyldiazenyl)-4,6-pyrimidinediamine 1H-Pyrazolo[3,4-b]pyridine, 5-fluoro-1-[(2-fluorophenyl)methyl]- 2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine 1H-Pyrazolo[3,4-b]pyridine-3-carboxylic acid, 5-fluoro-1-[(2-fluorophenyl)methyl]- Methyl N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methylcarbamate Velpatasvir Impurity 3 5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide

  • 5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
  • 5-fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
  • 1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 5-fluoro-1-[(2-fluorophenyl)methyl]-
  • 5-fluoro-1- (2-fluorobenzyl)- 1H1pyrazolo[3,4-b]pyridine-3- carbonitrile
  • 5-Fluoro-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-3-carbonitrile
  • 1350653-26-7
  • api
  • Intermediate