ChemicalBook > CAS DataBase List > 3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride (1:2)

3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride (1:2)

Product Name
3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride (1:2)
CAS No.
2050038-84-9
Chemical Name
3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride (1:2)
Synonyms
Upatinib N-1;Upadacitinib Impurity 43 DiHCl;Upadacitinib Impurity(Dihydrochloride);3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine;Upadacitinib Impurity 7(Dihydrochloride);8-((3R,4S)-4-ethylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine Hydrochloride;8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-3H-Imidazo[1,2-a]pyrrolo[ 2,3-e]pyrazine hydrochloride;8-((3R,4S)-4-ethylpyrrolidin-3-yl)-3h-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine dihydrocloride;8-((3R,4S)-4-ethylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine dihydrochloride;3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride
CBNumber
CB33357663
Molecular Formula
C14H18ClN5
Formula Weight
291.78
MOL File
2050038-84-9.mol
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3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride (1:2) Property

InChI
InChI=1/C14H17N5.ClH/c1-2-9-5-15-6-10(9)12-7-17-13-8-18-14-11(19(12)13)3-4-16-14;/h3-4,7-10,15-16H,2,5-6H2,1H3;1H/t9-,10+;/s3
InChIKey
KDRCTQDNHDFNKC-BTAGVKMCNA-N
SMILES
C([C@@H]1CNC[C@@H]1C1=CN=C2C=NC3NC=CC=3N12)C.Cl |&1:1,5,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride (1:2) Chemical Properties,Usage,Production

Uses

8-((3R,4S)-4-Ethylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine Dihydrochloride is a useful intermediate in the preparation of Upadacitinib, a JAK1 inhibitor.

3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride (1:2) Preparation Products And Raw materials

Raw materials

Preparation Products

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3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride (1:2) Suppliers

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View Lastest Price from 3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride (1:2) manufacturers

Moxin Chemicals
Product
Upadacitinib Impurity 7(Dihydrochloride) 2050038-84-9
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
95
Supply Ability
100000
Release date
2025-02-12
Anhui Dexinjia Biopharm Co., Ltd
Product
3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride (1:2) 2050038-84-9
Price
US $300.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
50kg per month
Release date
2023-04-02
ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Upadacitinib Impurity 7(Dihydrochloride) 2050038-84-9
Price
US $0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-03-28

2050038-84-9, 3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride (1:2)Related Search:

Lapatinib Cabozantinib LOXO-101 Dacomitinib (PF299804)

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  • 8-((3R,4S)-4-ethylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine Hydrochloride
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  • 8-((3R,4S)-4-ethylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine dihydrochloride
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  • 3H-Imidazo[1,2-a]pyrrolo[2,3-e]pyrazine, 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-, hydrochloride
  • Upadacitinib Impurity 7(Dihydrochloride)
  • Upadacitinib Impurity 43 DiHCl
  • 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-3H-Imidazo[1,2-a]pyrrolo[ 2,3-e]pyrazine hydrochloride
  • Upadacitinib Impurity(Dihydrochloride)
  • 8-((3R,4S)-4-ethylpyrrolidin-3-yl)-3h-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine dihydrocloride
  • 8-[(3R,4S)-4-ethyl-3-pyrrolidinyl]-3H-lmidazo[1,2-a]pyrrolo[2,3-e]pyrazine hydrochloride(1:2)
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  • 2050038-84-9