2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane

Product Name: 2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane
CAS No.: 1807503-91-8
Chemical Name: 2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane
Synonyms: AUN03918;C-NH-Boc-C-Bis-(C-PEG1-Boc);2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane;tert-butyl 3-[2-(tert-butoxycarbonylamino)-3-(3-tert-butoxy-3-oxo-propoxy)propoxy]propanoate;Propanoic acid, 3,3'-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-1,3-propanediyl]bis(oxy)]bis-, 1,1'-bis(1,1-dimethylethyl) ester
CBNumber: CB33363815
Molecular Formula: C22H41NO8
Formula Weight: 447.56
MOL File: 1807503-91-8.mol

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2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane Property

Boiling point:: 513.4±50.0 °C(Predicted)
Density: 1.055±0.06 g/cm3(Predicted)
pka: 11.51±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22629
Product name: 2-(t-Butoxycarbonylamido)-1,3-bis(t-butoxycarbonylethoxy)propane
Purity: 96%
Packaging: 500mg
Price: $230
Updated: 2021/12/16

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2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane Chemical Properties,Usage,Production

Biological Activity

C-NH-Boc-C-Bis-(C-PEG1-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane Suppliers

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1807503-91-8, 2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propaneRelated Search:

2-(t-Butoxycarbonylamido)-1,3-bis (t-butoxycarbonylethoxy)propane

C-NH-Boc-C-Bis-(C-PEG1-Boc)

Propanoic acid, 3,3'-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-1,3-propanediyl]bis(oxy)]bis-, 1,1'-bis(1,1-dimethylethyl) ester

AUN03918

tert-butyl 3-[2-(tert-butoxycarbonylamino)-3-(3-tert-butoxy-3-oxo-propoxy)propoxy]propanoate

1807503-91-8

C22H41NO8