Hydroxy-PEG3-SS-PEG3-alcohol

Product Name: Hydroxy-PEG3-SS-PEG3-alcohol
CAS No.: 5662-81-7
Chemical Name: Hydroxy-PEG3-SS-PEG3-alcohol
Synonyms: Hydroxy-PEG3-SS-PEG3-alcohol;3,6,9,16,19,22-Hexaoxa-12,13-dithiatetracosane-1,24-diol
CBNumber: CB33363941
Molecular Formula: C16H34O8S2
Formula Weight: 418.57
MOL File: 5662-81-7.mol

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Hydroxy-PEG3-SS-PEG3-alcohol Property

Boiling point:: 533.6±50.0 °C(Predicted)
Density: 1.183±0.06 g/cm3(Predicted)
solubility: Soluble in Water, DMSO, DMF, DCM
pka: 14.06±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22830
Product name: Hydroxy-PEG3-SS-PEG3-alcohol
Purity: 98%
Packaging: 100mg
Price: $380
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1446
Product name: Hydroxy-PEG3-SS-PEG3-alcohol
Packaging: 100mg
Price: $565
Updated: 2021/12/16

BroadPharm

Product number: BP-22830
Product name: Hydroxy-PEG3-SS-PEG3-alcohol
Purity: 98%
Packaging: 500mg
Price: $1020
Updated: 2021/12/16

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Hydroxy-PEG3-SS-PEG3-alcohol Chemical Properties,Usage,Production

Description

Hydroxy-PEG3-SS-PEG3-alcohol contains two terminal hydroxyl groups and a cleavable disulfide bond. The disulfide bond can be cleaved via reduction reactions using Dithiothreitol (DTT) reagent. The hydroxyl groups can be reacted to further derivatize the compound. The hydrophilic PEG chains increase the water solubility of the compound in aqueous media. The water solubility properties of the PEG linker are enhanced with longer PEG chains.

Uses

Hydroxy-PEG3-SS-PEG3-alcohol is also a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Disulfide Cleavable Linker; Cleavable Linker

References

[1] Barrientos AG, et al. Gold glyconanoparticles: synthetic polyvalent ligands mimicking glycocalyx-like surfaces as tools for glycobiological studies. Chemistry. 2003 May 9;9(9):1909-21. DOI:10.1002/chem.200204544

Hydroxy-PEG3-SS-PEG3-alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxy-PEG3-SS-PEG3-alcohol Suppliers

China 13 United Kingdom 1 United States 4 Global 18

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5662-81-7, Hydroxy-PEG3-SS-PEG3-alcoholRelated Search:

Hydroxy-PEG3-SS-PEG3-alcohol

3,6,9,16,19,22-Hexaoxa-12,13-dithiatetracosane-1,24-diol

5662-81-7