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Rbin-2 - Ribozinoindole-2

Product Name
Rbin-2 - Ribozinoindole-2
CAS No.
2032282-97-4
Chemical Name
Rbin-2 - Ribozinoindole-2
Synonyms
Rbin-2;Rbin 2,Rbin2;Rbin-2 >=98% (HPLC);Rbin-2 - Ribozinoindole-2;7-Bromo-3-((2-methylallyl)thio)-5H-[1,2,4]triazino[5,6-b]indole;5H-1,2,4-Triazino[5,6-b]indole, 7-bromo-3-[(2-methyl-2-propen-1-yl)thio]-
CBNumber
CB33364115
Molecular Formula
C13H11BrN4S
Formula Weight
335.22
MOL File
2032282-97-4.mol
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Rbin-2 - Ribozinoindole-2 Property

Boiling point:
524.3±60.0 °C(Predicted)
Density 
1?+-.0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 1mg/mL, clear (warmed)
form 
Solid
pka
9.30±0.50(Predicted)
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1865
Product name
Rbin-2
Purity
≥98% (HPLC)
Packaging
5 mg
Price
$121
Updated
2025/07/31
Axon Medchem
Product number
Axon2712
Product name
Rbin-2-Ribozinoindole-2
Purity
98%
Packaging
10mg
Price
$104.5
Updated
2021/12/16
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Rbin-2 - Ribozinoindole-2 Chemical Properties,Usage,Production

Description

Rbin-2 is a novel cell penetrant, potent, selective and reversible inhibitor of Midasin, inhibiting eukaryotic ribosome biogenesis and directly targeting AAA+ ATPase Midasin.

Uses

Rbin-2 is a potent, reversible and selective inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family. Rbin-2 inhibits eukaryotic ribosome biogenesis and is a powerful probe for the eukaryotic ribosome assembly[1].

References

[1] Kawashima SA, et al. Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis. Cell. 2016 Oct 6;167(2):512-524.e14. DOI:10.1016/j.cell.2016.08.070

Rbin-2 - Ribozinoindole-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Rbin-2 - Ribozinoindole-2 Suppliers

Nanjing Chemlin Chemical Co., Ltd
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025-83697070
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+86-25-83453306
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info@chemlin.com.cn
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China
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Bide Pharmatech Ltd.
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400-164-7117 13681763483
Fax
+86-21-61629029
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product02@bidepharm.com
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China
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39966
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Shanghai Haozhixiang Biotechnology Co., Ltd
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526763801 13301653310
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+86-21-51619052
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526763801@qq.com
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China
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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021-65675885
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info@efebio.com
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China
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9803
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Shanghai Chaolan Chemical Technology Center
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021-QQ:65489617 15618227136
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21-5161 9052
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Sales@ATKchemical.com
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China
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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32435
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Energy Chemical
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021-58432009 400-005-6266
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marketing@energy-chemical.com
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China
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Jinan Jiuli Biotechnology Co. , Ltd.
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15865264761
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486064515@qq.com
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China
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Wuhan Augda Biotechnology Co., Ltd
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15071299552
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QQ:262933239
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262933239@qq.com
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China
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7048
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Beijing Biocreative Technology Co., Ltd.
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15522676233
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3007606172@qq.com
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China
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2032282-97-4, Rbin-2 - Ribozinoindole-2Related Search:


  • Rbin-2 - Ribozinoindole-2
  • Rbin-2
  • 5H-1,2,4-Triazino[5,6-b]indole, 7-bromo-3-[(2-methyl-2-propen-1-yl)thio]-
  • Rbin-2 >=98% (HPLC)
  • Rbin 2,Rbin2
  • 7-Bromo-3-((2-methylallyl)thio)-5H-[1,2,4]triazino[5,6-b]indole
  • 2032282-97-4