ChemicalBook > CAS DataBase List > Rbin-2 - Ribozinoindole-2
Rbin-2 - Ribozinoindole-2
- Product Name
- Rbin-2 - Ribozinoindole-2
- CAS No.
- 2032282-97-4
- Chemical Name
- Rbin-2 - Ribozinoindole-2
- Synonyms
- Rbin-2;Rbin 2,Rbin2;Rbin-2 >=98% (HPLC);Rbin-2 - Ribozinoindole-2;7-Bromo-3-((2-methylallyl)thio)-5H-[1,2,4]triazino[5,6-b]indole;5H-1,2,4-Triazino[5,6-b]indole, 7-bromo-3-[(2-methyl-2-propen-1-yl)thio]-
- CBNumber
- CB33364115
- Molecular Formula
- C13H11BrN4S
- Formula Weight
- 335.22
- MOL File
- 2032282-97-4.mol
More
Less
Rbin-2 - Ribozinoindole-2 Property
- Boiling point:
- 524.3±60.0 °C(Predicted)
- Density
- 1?+-.0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 1mg/mL, clear (warmed)
- form
- Solid
- pka
- 9.30±0.50(Predicted)
- color
- Off-white to light yellow
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML1865
- Product name
- Rbin-2
- Purity
- ≥98% (HPLC)
- Packaging
- 5 mg
- Price
- $121
- Updated
- 2025/07/31
Axon Medchem
- Product number
- Axon2712
- Product name
- Rbin-2-Ribozinoindole-2
- Purity
- 98%
- Packaging
- 10mg
- Price
- $104.5
- Updated
- 2021/12/16
More
Less
Rbin-2 - Ribozinoindole-2 Chemical Properties,Usage,Production
Description
Rbin-2 is a novel cell penetrant, potent, selective and reversible inhibitor of Midasin, inhibiting eukaryotic ribosome biogenesis and directly targeting AAA+ ATPase Midasin.
Uses
Rbin-2 is a potent, reversible and selective inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family. Rbin-2 inhibits eukaryotic ribosome biogenesis and is a powerful probe for the eukaryotic ribosome assembly[1].
References
[1] Kawashima SA, et al. Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis. Cell. 2016 Oct 6;167(2):512-524.e14. DOI:10.1016/j.cell.2016.08.070
Rbin-2 - Ribozinoindole-2 Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
Rbin-2 - Ribozinoindole-2 Suppliers
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 15883
- Advantage
- 64
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 526763801 13301653310
- Fax
- +86-21-51619052
- 526763801@qq.com
- Country
- China
- ProdList
- 9274
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 021-QQ:65489617 15618227136
- Fax
- 21-5161 9052
- Sales@ATKchemical.com
- Country
- China
- ProdList
- 9125
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44918
- Advantage
- 58
- Tel
- 15865264761
- 486064515@qq.com
- Country
- China
- ProdList
- 4810
- Advantage
- 58
- Tel
- 15071299552
- Fax
- QQ:262933239
- 262933239@qq.com
- Country
- China
- ProdList
- 7048
- Advantage
- 58
- Tel
- 15522676233
- 3007606172@qq.com
- Country
- China
- ProdList
- 1248
- Advantage
- 58