DIIODOSILANE

DIIODOSILANE Property

Melting point:

-1°C

Boiling point:

56-60 °C/25 mmHg (lit.)

Density 

2.834 g/mL at 25 °C (lit.)

Flash point:

101 °F

storage temp. 

2-8°C

solubility 

highly sol hydrocarbons and chlorinated solvents; reacts with oxygen- and nitrogen-containing solvents.

form 

colorless liquid

Specific Gravity

2.834

color 

colorless

Hydrolytic Sensitivity

9: reacts extremely rapidly with atmospheric moisture - may be pyrophoric - glove box or sealed system required

InChI

InChI=1S/H2I2Si/c1-3-2/h3H2

InChIKey

AIHCVGFMFDEUMO-UHFFFAOYSA-N

SMILES

[SiH2](I)I

Safety

Hazard Codes 

C

Risk Statements 

10-14-20/21/22-34

Safety Statements 

16-26-27-28-36/37/39-45

RIDADR 

UN 3129 4.3/PG 1

WGK Germany 

3

TSCA 

No

HazardClass 

3.2

PackingGroup 

III

HS Code 

28129000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H260In contact with water releases flammable gases which may ignite spontaneously

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P231+P232Handle under inert gas. Protect from moisture.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

DIIODOSILANE Chemical Properties,Usage,Production

Chemical Properties

Clear liquid

Uses

Reagent involved in reductive iodination for synthesis of [18F]FDOPA

Preparation

Preparative Method of Diiodosilane: phenylsilane and iodine are mixed in a 1:1 molar ratio without solvent at -20 °C in the presence of catalytic amounts of ethyl acetate; fractional distillation removes volatile side products (benzene and HI) and affords the reagent in the form of a colorless oil.

General Description

Diiodosilane (DIS) is a strong, oxophilic Lewis acid, converts alcohols, ethers, and acetals to iodoalkanes; converts carboxylic acid derivatives to acyl iodides; mild reducing agent.

storage

Diiodosilane is sensitive to moisture; handle and store under nitrogen; stabilized by metallic copper; refrigeration and absence of light recommended for storage over long periods of time.