Prucalopride Impurity 1

Product Name: Prucalopride Impurity 1
CAS No.: 1900715-96-9
Chemical Name: Prucalopride Impurity 1
Synonyms: Prucalopride Impurity65;Prucalopride Impurity U;Prucalopride Impurity 04;Prucalopride Succinate iMpuritP;7-Benzofurancarboxamide, 4-amino-5-chloro-N-[1-(3-methoxypropyl)-4-piperidinyl]-;4-?Amino-?5-?chloro-?N-?[1-?(3-?methoxypropyl)?-?4-?piperidinyl]?-7-?benzofurancarboxamid?e
CBNumber: CB33368395
Molecular Formula: C18H24ClN3O3
Formula Weight: 365.85
MOL File: 1900715-96-9.mol

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Prucalopride Impurity 1 Property

Boiling point:: 527.2±50.0 °C(Predicted)
Density: 1.29±0.1 g/cm3(Predicted)
pka: 13.13±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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Prucalopride Impurity 1 Chemical Properties,Usage,Production

Uses

4-?Amino-?5-?chloro-?N-?[1-?(3-?methoxypropyl)?-?4-?piperidinyl]?-7-?benzofurancarboxamid?e is an impurity of Prucalopride Succinate (P838950(P)), which is a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe. In a more recent analytical study, 4-?Amino-?5-?chloro-?N-?[1-?(3-?methoxypropyl)?-?4-?piperidinyl]?-7-?benzofurancarboxamid?e was selectively separated and characterized as a process impurity of Prucalopride Succinate (P838950(P)) under stress conditions.

Prucalopride Impurity 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Prucalopride Impurity 1 Suppliers

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4-?Amino-?5-?chloro-?N-?[1-?(3-?methoxypropyl)?-?4-?piperidinyl]?-7-?benzofurancarboxamid?e

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Prucalopride Impurity U

1900715-96-9