N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide

Product Name: N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide
CAS No.: 1644069-80-6
Chemical Name: N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide
Synonyms: DDR Inhibitor;DDR Inhibitor, 10 mM in DMSO;N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide;N-[5-[[(3-fluorophenyl)carbamoylamino]methyl]-2-methylphenyl]imidazo[1,2-a]pyridine-3-carboxamide;Imidazo[1,2-a]pyridine-3-carboxamide, N-[5-[[[[(3-fluorophenyl)amino]carbonyl]amino]methyl]-2-methylphenyl]-
CBNumber: CB33370554
Molecular Formula: C23H20FN5O2
Formula Weight: 417.44
MOL File: 1644069-80-6.mol

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N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide Property

Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 65 mg/mL (155.71 mM);Water : < 0.1 mg/mL (insoluble)
form: Solid
pka: 12.87±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-W020277
Product name: DDRInhibitor
Purity: 97.85%
Packaging: 10mg
Price: $1029
Updated: 2021/12/16

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N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide Chemical Properties,Usage,Production

Uses

DDR Inhibitor is a potent discoidin domain receptor (DDR) inhibitor, with an IC50 of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM.

References

[1] Gordon Saxty, et al. Imidazo-condensed bicycles as inhibitors of discoidin domain receptors (ddrs)

N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide Suppliers

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1644069-80-6, N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamideRelated Search:

N-[5-[[(3-fluorophenyl)carbamoylamino]methyl]-2-methylphenyl]imidazo[1,2-a]pyridine-3-carboxamide

N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide

DDR Inhibitor

Imidazo[1,2-a]pyridine-3-carboxamide, N-[5-[[[[(3-fluorophenyl)amino]carbonyl]amino]methyl]-2-methylphenyl]-

DDR Inhibitor, 10 mM in DMSO

1644069-80-6