ChemicalBook > CAS DataBase List > N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide
N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide
- Product Name
- N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide
- CAS No.
- 1644069-80-6
- Chemical Name
- N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide
- Synonyms
- DDR Inhibitor;DDR Inhibitor, 10 mM in DMSO;N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide;N-[5-[[(3-fluorophenyl)carbamoylamino]methyl]-2-methylphenyl]imidazo[1,2-a]pyridine-3-carboxamide;Imidazo[1,2-a]pyridine-3-carboxamide, N-[5-[[[[(3-fluorophenyl)amino]carbonyl]amino]methyl]-2-methylphenyl]-
- CBNumber
- CB33370554
- Molecular Formula
- C23H20FN5O2
- Formula Weight
- 417.44
- MOL File
- 1644069-80-6.mol
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N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide Property
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 65 mg/mL (155.71 mM);Water : < 0.1 mg/mL (insoluble)
- form
- Solid
- pka
- 12.87±0.70(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-W020277
- Product name
- DDRInhibitor
- Purity
- 97.85%
- Packaging
- 10mg
- Price
- $1029
- Updated
- 2021/12/16
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N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide Chemical Properties,Usage,Production
Uses
DDR Inhibitor is a potent discoidin domain receptor (DDR) inhibitor, with an IC50 of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM.
References
[1] Gordon Saxty, et al. Imidazo-condensed bicycles as inhibitors of discoidin domain receptors (ddrs)
N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
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N-(5-((3-(3-fluorophenyl)ureido)methyl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide Suppliers
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