ChemicalBook > CAS DataBase List > Iodo-PEG3-Azide
Iodo-PEG3-Azide
- Product Name
- Iodo-PEG3-Azide
- CAS No.
- 936917-36-1
- Chemical Name
- Iodo-PEG3-Azide
- Synonyms
- I-PEG3-N3;Iodo-PEG3-N3;Iodo-PEG4-N3;Iodo-PEG3-Azide;Azido-PEG3-Iodine;1-Azido-2-(2-(2-(2-iodoethoxy)ethoxy)ethoxy)ethane;1-azido-2-(2-(2-(2-iodoethoxyl)ethoxy)ethoxy)ethane
- CBNumber
- CB33373636
- Molecular Formula
- C8H16IN3O3
- Formula Weight
- 329.14
- MOL File
- 936917-36-1.mol
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Iodo-PEG3-Azide Property
- storage temp.
- 2-8°C, protect from light
- form
- Liquid
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-23948
- Product name
- Iodo-PEG3-Azide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $350
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-23948
- Product name
- Iodo-PEG3-Azide
- Purity
- 98%
- Packaging
- 500mg
- Price
- $540
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-23948
- Product name
- Iodo-PEG3-Azide
- Purity
- 98%
- Packaging
- 1g
- Price
- $780
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 186179
- Product name
- Iodo-PEG3-azide
- Purity
- 95%
- Packaging
- 2.500g
- Price
- $1816
- Updated
- 2021/12/16
A1 Biochem Labs
- Product number
- 6575056
- Product name
- Iodo-PEG3-Azide
- Purity
- 95%
- Packaging
- 2.5g
- Price
- $1100
- Updated
- 2021/12/16
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Iodo-PEG3-Azide Chemical Properties,Usage,Production
Description
Iodo-PEG3-Azide is a PEG linker containing iodide and azide moieties. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The iodide is a very good leaving group for nucleophilic substitution reactions.
Uses
Iodo-PEG3-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Iodo-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Iodo-PEG3-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
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Iodo-PEG3-Azide Suppliers
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View Lastest Price from Iodo-PEG3-Azide manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Azido-PEG3-Iodine 936917-36-1
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-23