ChemicalBook > CAS DataBase List > 5α-Pregnane-3β,6α-diol-20-one

5α-Pregnane-3β,6α-diol-20-one

Product Name
5α-Pregnane-3β,6α-diol-20-one
CAS No.
21853-11-2
Chemical Name
5α-Pregnane-3β,6α-diol-20-one
Synonyms
5α-Pregnane-3β,6α-diol-20-one;5α-Pregnane-3β,6α-diol-20-one, 10 mM in DMSO;5αPregnane3β,6αdiol20one,5α Pregnane 3β,6α diol 20 one,inhibit,Inhibitor
CBNumber
CB33386443
Molecular Formula
C21H34O3
Formula Weight
334.49
MOL File
21853-11-2.mol
More
Less

5α-Pregnane-3β,6α-diol-20-one Property

Melting point:
202-203 °C
Boiling point:
469.7±30.0 °C(Predicted)
Density 
1.117±0.06 g/cm3(Predicted)
pka
14.72±0.70(Predicted)
form 
Solid
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

ChemScene
Product number
CS-0031562
Product name
5α-Pregnane-3β,6α-diol-20-one
Purity
>98.0%
Packaging
5mg
Price
$159
Updated
2021/12/16
ChemScene
Product number
CS-0031562
Product name
5α-Pregnane-3β,6α-diol-20-one
Purity
>98.0%
Packaging
10mg
Price
$271
Updated
2021/12/16
More
Less

5α-Pregnane-3β,6α-diol-20-one Chemical Properties,Usage,Production

Uses

5α-Pregnane-3β,6α-diol-20-one is a mitogenic metabolite of progesterone, and it can be produced in starved androgen-responsive prostate cancer cells.

References

[1] Zhang J, et al. Progesterone metabolism in human fibroblasts is independent of P-glycoprotein levels and Niemann-Pick type C disease. J Steroid Biochem Mol Biol. 1999 Sep-Oct;70(4-6):123-31. DOI:10.1016/s0960-0760(99)00107-7
[2] de Mello Martins AGG, et al. CYP17A1-independent production of the neurosteroid-derived 5α-pregnan-3β,6α-diol-20-one in androgen-responsive prostate cancer cell lines under serum starvation and inhibition by Abiraterone. J Steroid Biochem Mol Biol. 2017 Nov;174:183-191. DOI:10.1016/j.jsbmb.2017.09.006

5α-Pregnane-3β,6α-diol-20-one Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5α-Pregnane-3β,6α-diol-20-one Suppliers

China 14 United States 3 Global 17
Jurong Coupling Biotechnology Co., Ltd.
Tel
19231718652
Email
278191416@qq.com
Country
China
ProdList
482
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Changzhou Borl Biotechnology Co.,LTD
Tel
13606124132;13656121842
Email
luyan0021@163.com
Country
China
ProdList
235
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11973
Advantage
58
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6710
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58

21853-11-2, 5α-Pregnane-3β,6α-diol-20-oneRelated Search:


  • 5α-Pregnane-3β,6α-diol-20-one
  • 5αPregnane3β,6αdiol20one,5α Pregnane 3β,6α diol 20 one,inhibit,Inhibitor
  • 5α-Pregnane-3β,6α-diol-20-one, 10 mM in DMSO
  • 21853-11-2