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LAT-NET

Product Name
LAT-NET
CAS No.
607351-44-0
Chemical Name
LAT-NET
Synonyms
LAT-NET;Bimatoprost Impurity 20;LATANOPROST ETHYL AMIDE;13,14-Dihydro Bimatoprost;N-ETHYL-9ALPHA, 11ALPHA, 15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR PROST 5Z-EN-1-AMIDE;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethylhept-5-enamide;5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethyl-, (5Z)-
CBNumber
CB3344563
Molecular Formula
C25H39NO4
Formula Weight
417.58
MOL File
Mol file
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LAT-NET Property

Boiling point:
640.9±55.0 °C(Predicted)
Density 
1.095±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 50 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 200 μg/ml
pka
14.84±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16822
Product name
Latanoprost ethyl amide
Purity
≥98%
Packaging
1mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
16822
Product name
Latanoprost ethyl amide
Purity
≥98%
Packaging
5mg
Price
$324
Updated
2024/03/01
Cayman Chemical
Product number
16822
Product name
Latanoprost ethyl amide
Purity
≥98%
Packaging
10mg
Price
$575
Updated
2024/03/01
TRC
Product number
D450468
Product name
13,14-DihydroBimatoprost
Packaging
1mg
Price
$155
Updated
2021/12/16
AK Scientific
Product number
6557CR
Product name
Latanoprostethylamide
Packaging
10mg
Price
$737
Updated
2021/12/16
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LAT-NET Chemical Properties,Usage,Production

Description

Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity. Prostaglandin N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that prostaglandin ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. Lat-NEt would be expected to show the typical intraocular effects of Latanoprost free acid, but with the much slower hydrolysis pharmacokinetics of the prostaglandin N-amides.

Uses

13,14-Dihydro Bimatoprost can be used as reactant/reagent for preparation of nitrooxy prostamides for treatment of glaucoma. Analog or impurity of the drug Bimatoprost (B386800).

Definition

ChEBI: Latanoprost ethyl amide is a prostanoid.

LAT-NET Preparation Products And Raw materials

Raw materials

Preparation Products

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LAT-NET Suppliers

Canada 1 China 10 China Hong Kong 1 India 1 United States 1 Global 14
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd
Tel
0571-85361029
Fax
0571-85361029
Email
synstar518@163.com
Country
China
ProdList
1990
Advantage
58
Jinan blalong chemical co. LTD
Tel
2710913286@.com
Email
1513643261@qq.com
Country
China
ProdList
14246
Advantage
58
TopScience Biochemical
Tel
00852-68527855
Fax
00852-26406298
Email
info@itopbiochem.com
Country
China Hong Kong
ProdList
902
Advantage
58
Shenzhen Roark Pharma-Tec Co., Ltd.
Tel
13128912434
Email
2880126944@qq.com
Country
China
ProdList
2577
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58
Hubei Aiputi Bioengineering Co., Ltd.
Tel
17762444226
Email
d17762444226@163.com
Country
China
ProdList
2402
Advantage
58
Nanjing Tengyi Biotechnology Co., Ltd
Tel
025-58851786 17714337195
Email
sales@tybiochem.com
Country
China
ProdList
6813
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
Shanghai Zerui Biotechnology Co., Ltd.
Tel
021-54580889 18321124657
Fax
021-54580889
Email
731997554@qq.com
Country
China
ProdList
10608
Advantage
58

607351-44-0, LAT-NETRelated Search:

(Z)-7-[(1R,2R,3R,5S)-3,5-DIHYDROXY-2-((E)-(S)-3-HYDROXY-5-PHENYL-PENT-1-ENYL)-CYCLOPENTYL]-HEPT-5-ENOIC ACID METHYL ESTER (-)-Corey Lactone Diol (5-(ethylamino)-5-oxopentyl)triphenylphosphonium bromide 17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA Dimethyl (2-oxo-4-phenylbutyl)phosphonate 17- Phenyl Trinor Prostaglandin F2α Methyl Amide CHEMPACIFIC 59929 HYDRIDE-L 15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA Bimatoprost Impurity 9 Bimatoprost Impurity 17 Bimatoprost Impurity 15 Bimatoprost Impurity 22 Bimatoprost Impurity 13 Bimatoprost Impurity 2 (Mixture of Diastereomers) Bimatoprost Impurity 14 Bimatoprost Impurity 21 Bimatoprost Impurity 18

  • LATANOPROST ETHYL AMIDE
  • LAT-NET
  • N-ETHYL-9ALPHA, 11ALPHA, 15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR PROST 5Z-EN-1-AMIDE
  • 13,14-Dihydro Bimatoprost
  • (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethylhept-5-enamide
  • Bimatoprost Impurity 20
  • 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethyl-, (5Z)-
  • 607351-44-0
  • C25H39NO4