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Ceftriaxone sodium

Product Name
Ceftriaxone sodium
CAS No.
104376-79-6
Chemical Name
Ceftriaxone sodium
Synonyms
Rosihlitazone;CEFTRIAXONE NA;RO-13-9904/001;Hemiheptahydrate;ROCEFIN ROCEPHINE;CEFTRIASONE SODIUM;CEFTRIAXONE SODIUM INJ;Ceftriaxone sodium CRS;CEFTRIAXONE SODIUM SALT;CEFTRIAXONE SODIUM HYDRATE
CBNumber
CB3350760
Molecular Formula
C18H21N8NaO8S3
Formula Weight
596.58
MOL File
104376-79-6.mol
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Ceftriaxone sodium Property

Melting point:
236 °C
alpha 
D25 -165° (c = 1 in water) (calc for water-free substance)
refractive index 
-160 ° (C=1, H2O)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
H2O: soluble50mg/mL
pka
~3 (COOH), 3.2 (NH3+), 4.1 (enolic OH)
form 
powder or crystals
color 
White to Off-White
Water Solubility 
Freely soluble in water
InChIKey
FDRNWTJTHBSPMW-BBJOQENWSA-L
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-42/43
Safety Statements 
26-36-45-37-24-22
WGK Germany 
1
RTECS 
XI0368800
HS Code 
29349990
Toxicity
LD50 in male, female, mice, rats (mg/kg): 3000, 2800, 2175, 2175 i.v.; >10000 all species orally; >5000 all species s.c. (Teelman)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C5793
Product name
Ceftriaxone disodium salt hemi(heptahydrate)
Purity
third-generation cephalosporin antibiotic
Packaging
1g
Price
$351
Updated
2024/03/01
Sigma-Aldrich
Product number
1098184
Product name
Ceftriaxone sodium
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
350mg
Price
$436
Updated
2024/03/01
TCI Chemical
Product number
C2226
Product name
Ceftriaxone Disodium Salt Hemiheptahydrate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$91
Updated
2024/03/01
TCI Chemical
Product number
C2226
Product name
Ceftriaxone Disodium Salt Hemiheptahydrate
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$263
Updated
2024/03/01
Alfa Aesar
Product number
J66003
Product name
Ceftriaxone sodium hemiheptahydrate, 98%
Packaging
250mg
Price
$72.65
Updated
2024/03/01
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Ceftriaxone sodium Chemical Properties,Usage,Production

Description

Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models.

Chemical Properties

White Crystalline Solid

Uses

antipsychotic

Uses

A potentially useful antibacterial agent for proteomics research.

Uses

An antibacterial, a third-generation cephalosporin.

Definition

ChEBI: Ceftriaxone disodium salt hemiheptahydrate is a cephalosporin.

brand name

Rocephin (Roche).

Biological Activity

β -lactam antibiotic. Displays neuroprotective activity in vivo via upregulation and increased activity of the EAAT2 glutamate transporter.

Ceftriaxone sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ceftriaxone sodium manufacturers

Hebei Kingfiner Technology Development Co.Ltd
Product
Ceftriaxone sodium 104376-79-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000kg
Release date
2023-11-22
Hebei Mojin Biotechnology Co., Ltd
Product
Ceftriaxone sodium 104376-79-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-20
Hebei Guanlang Biotechnology Co., Ltd.
Product
Ceftriaxone Sodium 104376-79-6
Price
US $1.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10mt
Release date
2021-01-29

104376-79-6, Ceftriaxone sodiumRelated Search:


  • (6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-Methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]Methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid SodiuM Salt Hydrate
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  • 104376-79-6
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