ChemicalBook > CAS DataBase List > Ceftriaxone sodium

Ceftriaxone sodium

Product Name: Ceftriaxone sodium
CAS No.: 104376-79-6
Chemical Name: Ceftriaxone sodium
Synonyms: Rosihlitazone;CEFTRIAXONE NA;RO-13-9904/001;Hemiheptahydrate;ROCEFIN ROCEPHINE;CEFTRIASONE SODIUM;Ceftriaxone （USP34 ）;Ceftriaxone Sodium RS;CEFTRIAXONE SODIUM INJ;Ceftriaxone sodium CRS
CBNumber: CB3350760
Molecular Formula: C18H21N8NaO8S3
Formula Weight: 596.58
MOL File: 104376-79-6.mol

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Ceftriaxone sodium Property

Melting point:: 236 °C
alpha: D25 -165° (c = 1 in water) (calc for water-free substance)
refractive index: -160 ° (C=1, H2O)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: H2O: soluble50mg/mL
pka: ~3 (COOH), 3.2 (NH3+), 4.1 (enolic OH)
form: powder or crystals
color: White to Off-White
Water Solubility: Freely soluble in water
InChIKey: FDRNWTJTHBSPMW-BBJOQENWSA-L
SMILES: C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)CSC1=NC(=O)C(=O)NN1C)(=O)O.[NaH].O |&1:5,7,r|

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Safety

Hazard Codes: Xn
Risk Statements: 36/37/38-42/43
Safety Statements: 26-36-45-37-24-22
WGK Germany: 1
RTECS: XI0368800
HS Code: 29349990
Toxicity: LD50 in male, female, mice, rats (mg/kg): 3000, 2800, 2175, 2175 i.v.; >10000 all species orally; >5000 all species s.c. (Teelman)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C5793
Product name: Ceftriaxone disodium salt hemi(heptahydrate)
Purity: third-generation cephalosporin antibiotic
Packaging: 1g
Price: $361
Updated: 2025/07/31

Sigma-Aldrich

Product number: C0691000
Product name: Ceftriaxone sodium
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 100 mg
Price: $236
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1098184
Product name: Ceftriaxone sodium
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 350mg
Price: $425
Updated: 2025/07/31

TCI Chemical

Product number: C2226
Product name: Ceftriaxone Disodium Salt Hemiheptahydrate
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $87
Updated: 2025/07/31

TCI Chemical

Product number: C2226
Product name: Ceftriaxone Disodium Salt Hemiheptahydrate
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $250
Updated: 2025/07/31

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Ceftriaxone sodium Chemical Properties,Usage,Production

Description

Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models.

Chemical Properties

White Crystalline Solid

Uses

antipsychotic

Uses

A potentially useful antibacterial agent for proteomics research.

Uses

An antibacterial, a third-generation cephalosporin.

Definition

ChEBI: Ceftriaxone disodium salt hemiheptahydrate is a cephalosporin.

brand name

Rocephin (Roche).

Biological Activity

β -lactam antibiotic. Displays neuroprotective activity in vivo via upregulation and increased activity of the EAAT2 glutamate transporter.

References

[1] H. NEU F KWUNGP N Meropol. Antibacterial Activity of Ceftriaxone (Ro 13-9904), a β-Lactamase-Stable Cephalosporin[J]. Antimicrobial Agents and Chemotherapy, 1981, 19 1: 940-940. DOI: 10.1128/aac.19.5.940-b
[2] SIZHUANG YAN Dennis L S Paul M Mendelman. The in vitro antibacterial activity of ceftriaxone against Streptococcus pyogenes is unrelated to penicillin-binding protein 4[J]. Fems Microbiology Letters, 1993, 110 3: Pages 313-317.

Ceftriaxone sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ceftriaxone sodium manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Ceftriaxone Sodium 104376-79-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-12-09

Sinoway Industrial co., ltd.

Product: Ceftriaxone sodium 104376-79-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2024-05-15

Hebei Chuanghai Biotechnology Co., Ltd

Product: Ceftriaxone Sodium 104376-79-6
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10mt
Release date: 2025-03-10

104376-79-6, Ceftriaxone sodiumRelated Search:

(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Thiotriazinone Cephalothin sodium Cefotaxime sodium 3-Desacetyl CefotaxiMe Lactone (E)-Ceftriaxone Ceftriaxone Sodium intermediate CEFTRIAXONE SODIUM, USP Ceftriaxone sodium CEFTRIAXONE IMPURITY A CEFTRIAXONE SODIUM E-ISOMER (25 MG) Ceftriaxone Sodium sterile USP/EP/JP Ceftriaxone sodium Non sterile(crude) Ceftriaxone sodium (crude) In-house Spec 25kg/box Ceftriaxone sodium (solvent crystallization of sterile BPC) CHP 、USP、EP 5kg/tin、2tin/box Ceftriaxone sodium crude,non-sterile,crystalline,sterile Ceftriaxone sodium crystalline.sterile 7-ACT / for Ceftriaxone Sodium

(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-Methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]Methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid SodiuM Salt Hydrate

Ceftriaxone sodiuM sesquaterhydrate

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, sodium salt, hydrate (2:4:7), (6R,7R)-

Ceftriaxone SodiuM Trihydrate

Ceftriaxone disodium salt hemiheptahydrate, >=98%

sodium 7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[(2-methyl-5,6-dioxo-1H-1,2,4-triazin-3-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Ceftriaxone (sodium salt hydrate)

Ceftriaxone Disodium Salt&nbsp

Hemiheptahydrate

Ceftriaxone hemi(heptahydrate) disodium salt

CEFTRIASONE SODIUM

Rosihlitazone

[6R-[6α,7β(Z)]]-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt

(6R,7R)-7-[(Z)-2-2(2-Amino-4-thiazolyl)-2-(methoxyimino)azetamido]-3-{[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazin-3-yl)thio]methyl}-8-oxo-5-thia-1-aza-bicyclo-[4.2.0]oct-2-en-2-carbonsure-dinatriumsalz

Disodium salt hemiheptahydrate

7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicaciddisodiumsalt

Ceftriaxone Sodium (350 mg)G1D265925ug/mg(an)

Ceftriaxone Sodium (350 mg)

CEFTRIAXONE, DISODIUM SALT, HEMIHEPTAHYDRATE

CEFTRIAXONE NA

CEFTRIAXONE SODIUM HYDRATE

CEFTRIAXONE SODIUM SALT

(6r,7r)-7-[2-(2-amino-4-thiazolyl)glyoxylamido]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt

ROCEFIN ROCEPHINE

RO-13-9904/001

CeftriaxoneSodiumSterileUsp26

Ro-13-9904/001, Rocefin Rocephine

CEFTRIAXONE SODIUM FOR INJECTION

CEFTRIAXONE SODIUM INJ

Ceftriaxone Sodium(Nonsterile)

Ceftriaxone sodium sterile

Ceftriaxone Disodium Salt Hemiheptahydrate Standard

Ceftriaxone sodium CRS

Ceftriaxone Sodium Hemiheptahydrate

Ceftriaxone Disodium Salt Hemiheptahydrate&gt

Ceftriaxone disodium hemiheptahydrate

(6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, disodium salt,Hemiheptahydrate

Ceftriaxone sodium hydrate (2:4:7)

Ceftriaxone sodium USP/EP/BP

Ceftriaxone disodium hemiheptahydrate, 5...

Ceftriaxone Disodium Salt Hemiheptahydrate (CFTZ)

Ceftriaxone Sodium (1098184)

Ceftriaxone Sodium Trihydrate|||Ceftriaxone disodium hemiheptahydrate|||Ceftriaxone sodium

Ceftriaxone disodium salt hemiheptahydrate in acetonitrile

Ceftriaxone disodium salt hemiheptahydrate in methanol

Ceftriaxone sodium 3.5 hydrate

Ceftriaxone disodium salt hemi(heptahydrate), beta-Lactam antibiotic

Ceftriaxone sodium hydrate, 10 mM in DMSO

Ceftriaxone sodium hydrate - Bio-X ?

Ceftriaxone （USP34 ）

Ceftriaxone Sodium RS

Ceftriaxone Sodium Hemitrihydrate

104376-79-6

74578-59-1

12-95-1

C18H16N8O7S372H2O2Na

C18H17N8NaO7S3