IXAQOQZEOGMIQS-YUMLLTTFSA-N
- Product Name
- IXAQOQZEOGMIQS-YUMLLTTFSA-N
- CAS No.
- 1622429-53-1
- Chemical Name
- IXAQOQZEOGMIQS-YUMLLTTFSA-N
- Synonyms
- Lipoxin A4-d5;IXAQOQZEOGMIQS-YUMLLTTFSA-N;Lipoxin A4-d5 MaxSpecStandard
- CBNumber
- CB33574868
- Molecular Formula
- C20H32O5
- Formula Weight
- 352.47
- MOL File
- 1622429-53-1.mol
IXAQOQZEOGMIQS-YUMLLTTFSA-N Property
- storage temp.
- Store at -80°C
- solubility
- DMF: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 10007737
- Product name
- Lipoxin A4-d5
- Purity
- ≥99% deuterated forms (d1-d5)
- Packaging
- 10μg
- Price
- $191
- Updated
- 2024/03/01
- Product number
- 10007737
- Product name
- Lipoxin A4-d5
- Purity
- ≥99% deuterated forms (d<sub>1</sub>-<wbr/>d<sub>5</sub>)
- Packaging
- 25μg
- Price
- $454
- Updated
- 2024/03/01
- Product number
- 10007737
- Product name
- Lipoxin A4-d5
- Purity
- ≥99% deuterated forms (d<sub>1</sub>-<wbr/>d<sub>5</sub>)
- Packaging
- 50μg
- Price
- $859
- Updated
- 2024/03/01
- Product number
- 10007737
- Product name
- Lipoxin A4-d5
- Purity
- ≥99% deuterated forms (d<sub>1</sub>-<wbr/>d<sub>5</sub>)
- Packaging
- 100μg
- Price
- $1523
- Updated
- 2024/03/01
- Product number
- 24936
- Product name
- Lipoxin A4-d5 MaxSpec? Standard
- Purity
- >95%
- Packaging
- 10μg
- Price
- $255
- Updated
- 2023/06/20
IXAQOQZEOGMIQS-YUMLLTTFSA-N Chemical Properties,Usage,Production
Uses
Lipoxin A4-d5 Sodium Salt is a labelled analog of Lipoxin A4 (L468775), which is a trihydroxy fatty acid produced through 15-HETE metabolism.
Biological Activity
Lipoxin A4-d5 (LXA4-d5) contains five deuterium atoms at the 19, 19', 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of LXA4 by GC- or LC-mass spectrometry (MS). LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes.1 LXA4 is equipotent to leukotriene B4 (LTB4) in inducing superoxide generation in human neutrophils at 0.1 μM.2 LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.2,3,4
References
1.Serhan, C.N., Nicolaou, K.C., Webber, S.E., et al.Lipoxin A. Stereochemistry and biosynthesisJ. Biol. Chem.261(35)16340-16345(1986) 2.Serhan, C.N., Hamberg, M., and Samuelsson, B.Lipoxins: Novel series of biologically active compounds formed from arachidonic acid in human leukocytesProc. Natl. Acad. Sci. U.S.A.81(17)5335-5339(1984) 3.Ramstedt, U., Serhan, C.N., Nicolaou, K.C., et al.Lipoxin A-induced inhibition of human natural killer cell cytotoxicity: Studies on stereospecificity of inhibition and mode of actionJ. Immunol.138(1)266-270(1987) 4.Maddox, J.F., and Serhan, C.N.Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: Selective inactivation by dehydrogenation and reductionJ. Exp. Med.183(1)137-146(1996)
IXAQOQZEOGMIQS-YUMLLTTFSA-N Preparation Products And Raw materials
Raw materials
Preparation Products
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