ChemicalBook > CAS DataBase List > 4-Vinylphenol

4-Vinylphenol

Product Name: 4-Vinylphenol
CAS No.: 2628-17-3
Chemical Name: 4-Vinylphenol
Synonyms: 4-VINYLPHENOL;p-hydroxystyrene;4-ethenylphenol;FEMA 3739;p-vinylphenol;4-vinylphenol,4-ethenyl-phenol,p-hydroxystyrene;p-Oxystyrene;Styrene-4-ol;p-vinyl-pheno;p-vinyl-phenol
CBNumber: CB3362136
Molecular Formula: C8H8O
Formula Weight: 120.15
MOL File: 2628-17-3.mol

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4-Vinylphenol Property

Melting point:: 73 °C
Boiling point:: 228.85°C (estimate)
Density: 1.04
vapor pressure: 9.38hPa at 25℃
FEMA: 3739 | P-VINYLPHENOL
refractive index: 1.4440
Flash point:: >230 °F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform (Sparingly), DMSO (Slightly)
form: Liquid
pka: 9.95±0.26(Predicted)
color: Clear colorless to orange
Odor: at 0.01 % in propylene glycol. chemical phenolic medicinal sweet
Odor Type: phenolic
Water Solubility: Slightly miscible with water.
Sensitive: Hygroscopic
JECFA Number: 711
BRN: 506844
Stability:: Light Sensitive
LogP: 2.3 at 25℃
CAS DataBase Reference: 2628-17-3(CAS DataBase Reference)
NIST Chemistry Reference: 4-hydroxystyrene(2628-17-3)
EPA Substance Registry System: Phenol, 4-ethenyl- (2628-17-3)

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
Safety Statements: 26-39
WGK Germany: 2
RTECS: SN3800000
HS Code: 29089990
Toxicity: rabbit,LDLo,ocular,50mg/kg (50mg/kg),United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-1285-0579S,

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H318Causes serious eye damage
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: V0215
Product name: 4-Vinylphenol
Purity: min. 98.0 %
Packaging: 1G
Price: $96
Updated: 2025/07/31

TCI Chemical

Product number: V0215
Product name: 4-Vinylphenol
Purity: min. 98.0 %
Packaging: 5G
Price: $288
Updated: 2025/07/31

TCI Chemical

Product number: V0088
Product name: 4-Vinylphenol (ca. 10% in Propylene Glycol)
Packaging: 5G
Price: $54
Updated: 2025/07/31

TCI Chemical

Product number: V0088
Product name: 4-Vinylphenol (ca. 10% in Propylene Glycol)
Packaging: 25G
Price: $162
Updated: 2025/07/31

TRC

Product number: V453313
Product name: 4-Vinylphenol,10wt.%InPropyleneGlycol
Packaging: 100mg
Price: $85
Updated: 2021/12/16

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4-Vinylphenol Chemical Properties,Usage,Production

Chemical Properties

4-Hydroxystyrene, also known as 4-vinylphenol or p-vinylphenol, is a colorless liquid with a vanilla extract odor. It can be dissolved in various organic solvents such as ethanol, acetone, benzene, and dimethyl sulfoxide, but it does not dissolve in water. This compound exhibits good stability, although it can be affected by light and ozone exposure, leading to potential oxidization reactions. It is an important chemical used as a monomer for producing poly(4-vinylphenol) (PVPh).

Occurrence

4-Vinylphenol is found in wine and beer. It is produced by the spoilage yeast Brettanomyces. When it reaches concentrations greater than the sensory threshold, it can give the wine aromas described as barnyard, medicinal, band-aids, and mousy. In wine, 4-vinylphenol can react with other molecules, such as anthocyanidins, to produce new chemical compounds. In white wines vinylphenols are dominant (4-vinylphenol 70-1 150 μg/l, 4-vinylguaiacol 10-490 μg/l) whereas, in red wines, it is the corresponding ethyl phenols.
Reported found in apple, cooked asparagus, dried bonito fish, cloudberries, cooked corn, roasted peanuts, rice bran, sandalwood, wild strawberries, vetiver oil, cooked apple, black currant, red wine, white wine, rose wine, coffee, green tea cognac, tomato, partially fermented tea, microbial fermented tea, black tea, heated soybean, coriander seeds, beer, cognac, peanut butter, soybean, beans, mushrooms, starfruit, tamarind, mango, rice, sweet corn, corn oil, malt, wort, rosemary and Bourbon vanilla.

Uses

4-Vinylphenol, 10 wt.% In Propylene Glycol can be used as a perfume oil mixture.

Definition

ChEBI: 4-hydroxystyrene is a member of the class of phenols that is styrene carrying a hydroxy substituent at position 4. It has a role as a human urinary metabolite and a human xenobiotic metabolite. It derives from a hydride of a styrene.

Production Methods

4-Hydroxystyrene (mp 73.5 C, sublimation range 70–80 ℃ at 0.004 kPa) can be obtained by gas-phase dehydrogenation of 4- ethylphenol at 550–600 ℃ and 0.1 MPa on an iron oxide catalyst and in the presence of steam and an aromatic hydrocarbon as diluents. The alkenylphenol, which polymerizes readily, can be separated from the less acidic unconverted 4-ethylphenol by extracting the condensed reactor effluent with alkali at 30 ℃.

Application

4-Vinylphenols, a class of functionalized styrenes, constitute one of the most extensively explored compounds due to their wide-ranging applications in food and alcoholic beverages, flavoring substances, and as intermediates in the preparation of various bioactive molecules, polymers, and copolymers that are useful in coatings, electronic applications, ion exchange resins, and photoresists, etc. In addition, several biological activities, such as antioxidant, antibacterial, antifungal, hypolipidemic, and antimutagenic, have been attributed to these compounds[1].

Aroma threshold values

Detection: 10 to 85 ppb

Taste threshold values

Taste characteristics at 60 ppm: phenolic, medicinal with sweet musty and meaty nuances.

Flammability and Explosibility

Not classified

References

[1] Arun K. Sinha, Bhupendra P. Joshi, Anuj Sharma. “One-Pot Two-Step Synthesis of 4-Vinylphenols from 4-Hydroxy Substituted Benzaldehydes under Microwave Irradiation: A New Perspective on the Classical Knoevenagel—Doebner Reaction.” ChemInform 38 19 (2007).

4-Vinylphenol Preparation Products And Raw materials

Raw materials

4-tert-Butylcatechol Hexane Copper Quinoline Acetic anhydride Sodium borohydride 4-Hydroxybenzaldehyde Hydroquinone Diethyl ether Aniline 4'-Hydroxyacetophenone Propylene glycol Pyridine Isopropyl alcohol Benzoyl chloride Potassium bisulfate Malonic acid

Preparation Products

S-(-)-Carbidopa

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View Lastest Price from 4-Vinylphenol manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 4-Vinylphenol 2628-17-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98
Supply Ability: 10000KGS
Release date: 2025-12-01

Shaanxi Dideu New Materials Co. Ltd

Product: 4-Vinylphenol 2628-17-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-12-01

Shaanxi Didu New Materials Co. Ltd

Product: 4-Vinylphenol 2628-17-3
Price: US $1.50/g
Min. Order: 1g
Purity: 99.0% Min
Supply Ability: 100 Tons
Release date: 2025-09-20

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p-vinylphenol

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4-hydroxystyrene (4-vinylphenol)

4-Vinylphenol, 10 wt.% In propylene glycol

High Quality 4-Hydroxystyrene CAS: 2628-17-3 China Supplier

Fast Delivery High Quality 4-Hydroxystyrene CAS 2628-17-3

Esmolol Impurity 34

4-Hydroxystyrene solution

Esmolol Impurity 26

4-Vinylphenol,10% Propylene glycol solution

4-ethenylphenol(IUPAC name)4-vinylphenol(Wiki)

4-hydrostyrene 4-Vinylphenol

2628-17-3

Aromatic Phenols

2628-17-3