ChemicalBook > CAS DataBase List > MST-312
MST-312
- Product Name
- MST-312
- CAS No.
- 368449-04-1
- Chemical Name
- MST-312
- Synonyms
- MST-312;MST-312 >=98% (HPLC);MST-312, 10 mM in DMSO;TELOMERASE INHIBITOR IX;N,N'-(1,3-Phenylene)bis(2,3-dihydroxybenzamide);Benzamide, N,N'-1,3-phenylenebis[2,3-dihydroxy-;N,N′-1,3-Phenylenebis-[2,3-dihydroxy-benzamide];N,N'-BIS(2,3-DIHYDROXYBENZOYL)-1,3-PHENYLENEDIAMINE;Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem;N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide
- CBNumber
- CB3366639
- Molecular Formula
- C20H16N2O6
- Formula Weight
- 380.35
- MOL File
- 368449-04-1.mol
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MST-312 Property
- Boiling point:
- 526.7±50.0 °C(Predicted)
- Density
- 1.578±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥20mg/mL
- form
- White solid
- pka
- 7.70±0.35(Predicted)
- color
- off-white to light tan
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- M3949
- Product name
- MST-312
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $118
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 581011
- Product name
- Telomerase Inhibitor IX
- Packaging
- 10mg
- Price
- $187
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 24301
- Product name
- MST-312
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 24301
- Product name
- MST-312
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $166
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- M3949
- Product name
- MST-312
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $379
- Updated
- 2024/03/01
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MST-312 Chemical Properties,Usage,Production
Uses
MST-312 has been used in cell invasion assay using mouse fibroblast cells (NIH-3T3) and in the co-immunoprecipitation experiments in colon fibroblast.
Definition
ChEBI: N-[3-[[(2,3-dihydroxyphenyl)-oxomethyl]amino]phenyl]-2,3-dihydroxybenzamide is a member of benzamides.
General Description
A cell-permeable, bis-catechol containing, m-phenylenediamide compound that displays anti-proliferative properties. Acts as a potent, reversible inhibitor of telomerase activity (IC50 = 670 nM, TRAP lysate prepared from U937 cells). Prolonged treatment with MST-312 has been reported to result in telomere shortening and growth arrest in U937 cells. Does not inhibit the activity of Taq DNA polymerase (IC50 >3 μM).
Biochem/physiol Actions
Cell permeable: yes
MST-312 Preparation Products And Raw materials
Raw materials
Preparation Products
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