2,4-DICHLORO-8-METHOXYQUINOLINE
- Product Name
- 2,4-DICHLORO-8-METHOXYQUINOLINE
- CAS No.
- 32608-29-0
- Chemical Name
- 2,4-DICHLORO-8-METHOXYQUINOLINE
- Synonyms
- 2,4-DICHLORO-8-METHOXYQUINOLINE;Quinoline, 2,4-dichloro-8-methoxy-
- CBNumber
- CB3367474
- Molecular Formula
- C10H7Cl2NO
- Formula Weight
- 228.07
- MOL File
- 32608-29-0.mol
2,4-DICHLORO-8-METHOXYQUINOLINE Property
- Melting point:
- 92 °C
- Boiling point:
- 327.9±37.0 °C(Predicted)
- Density
- 1.384±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -2.83±0.50(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D437720
- Product name
- 2,4-Dichloro-8-methoxyquinoline
- Packaging
- 10mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 8659BB
- Product name
- 2,4-Dichloro-8-methoxyquinoline
- Packaging
- 100mg
- Price
- $231
- Updated
- 2021/12/16
- Product number
- 4H07-5-15
- Product name
- 2,4-Dichloro-8-methoxyquinoline
- Packaging
- 1g
- Price
- $965
- Updated
- 2021/12/16
- Product number
- 4H07-5-15
- Product name
- 2,4-Dichloro-8-methoxyquinoline
- Packaging
- 2g
- Price
- $1525
- Updated
- 2021/12/16
- Product number
- HCH0343965
- Product name
- 2,4-DICHLORO-8-METHOXYQUINOLINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.61
- Updated
- 2021/12/16
2,4-DICHLORO-8-METHOXYQUINOLINE Chemical Properties,Usage,Production
Synthesis
141-82-2
90-04-0
32608-29-0
The general synthetic route of the compound is schematically described in Scheme 1.The synthesis of 2,4-dichloro-8-methoxyquinoline was carried out with reference to literature reports [27,28] as follows: equimolar o-methoxyaniline and malonic acid were mixed with 30 mL of phosphorochloridic acid and refluxed for 5 h on a heating mantle kept at 80-100°C. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was cooled to room temperature and slowly poured into crushed ice with continuous stirring. The precipitated solid was separated by filtration, dried and washed thoroughly with water. The crude product was purified by column chromatography (eluent ratio 95:5 hexane-ethyl acetate) to afford 2,4-dichloro-8-methoxyquinoline in 78.6% yield.
References
[1] Journal of Molecular Structure, 2017, vol. 1131, p. 51 - 72
[2] Research on Chemical Intermediates, 2014, vol. 40, # 5, p. 1851 - 1866
[3] Medicinal Chemistry, 2015, vol. 11, # 8, p. 789 - 797
[4] Organic Process Research and Development, 2016, vol. 20, # 2, p. 215 - 226
[5] Journal of Organic Chemistry, 2013, vol. 78, # 21, p. 10605 - 10616
2,4-DICHLORO-8-METHOXYQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
2,4-DICHLORO-8-METHOXYQUINOLINE Suppliers
- Tel
- 8485655694
- sales@alchempharmtech.com
- Country
- United States
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- 63687
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- 58
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- tp@aladdinsci.com
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- United States
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- 52923
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- --
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- sales@combi-blocks.com
- Country
- United States
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- 6618
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- Tel
- --
- Fax
- --
- info@synquestlabs.com
- Country
- United States
- ProdList
- 6871
- Advantage
- 62
View Lastest Price from 2,4-DICHLORO-8-METHOXYQUINOLINE manufacturers
- Product
- 2,4-DICHLORO-8-METHOXYQUINOLINE 32608-29-0
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 85.0-99.8%
- Supply Ability
- 20tons
- Release date
- 2020-11-09