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NUARIMOL

Product Name
NUARIMOL
CAS No.
63284-71-9
Chemical Name
NUARIMOL
Synonyms
murox;el228;C11185;el2289;Trimiol;TRIMIDAL;NUARIMOL;triminol;guantlet;trimifruitsc
CBNumber
CB3375554
Molecular Formula
C17H12ClFN2O
Formula Weight
314.74
MOL File
63284-71-9.mol
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NUARIMOL Property

Melting point:
126°C
Boiling point:
475.2±40.0 °C(Predicted)
Density 
1.3255 (estimate)
vapor pressure 
1 x 10-5 Pa at 23 °C
storage temp. 
0-6°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
11.37±0.29(Predicted)
Water Solubility 
26 mg l-1 (pH 7) at 25 °C
color 
White to Pale Yellow
BRN 
6223667
InChI
InChI=1S/C17H12ClFN2O/c18-16-4-2-1-3-15(16)17(22,13-9-20-11-21-10-13)12-5-7-14(19)8-6-12/h1-11,22H
InChIKey
SAPGTCDSBGMXCD-UHFFFAOYSA-N
SMILES
C(O)(C1C=NC=NC=1)(C1C=CC(F)=CC=1)C1=CC=CC=C1Cl
EPA Substance Registry System
Nuarimol (63284-71-9)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26
WGK Germany 
3
RTECS 
UV9279700
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CRM31116
Product name
Nuarimol
Purity
certified reference material, TraceCERT?, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Packaging
50MG
Price
$64.9
Updated
2025/07/31
Sigma-Aldrich
Product number
31116
Product name
Nuarimol
Purity
PESTANAL
Packaging
100mg
Price
$51
Updated
2025/07/31
TRC
Product number
N925320
Product name
Nuarimol
Packaging
100mg
Price
$520
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
NUC0001069
Product name
NUARIMOL
Purity
95.00%
Packaging
5G
Price
$909.56
Updated
2021/12/16
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NUARIMOL Chemical Properties,Usage,Production

Uses

Nuarimol is a systemic fungicide with both curative and protective activity. It controls a wide range of pathogenic fungi, e.g. Cercosporella spp., Septoria spp., Ustilago spp., powdery mildews, leaf spot, etc. in cereals (as a foliar spray and as a seed treatment), powdery mildews on pome fruits, stone fruits, vines, cucurbits and other crops and scab on apples.

Uses

Nuarimol is used in the preparation of difluoroethyl-containing heterocyclic compounds useful as antiviral agents and fungicides. Also used as a substance in the modelling inhibition of avian aromatase by azole pesticides.

Metabolic pathway

Photolytic degradation is the primary dissipation mechanism of nuarimol in the environment. Major degradation reactions observed on plants/soil surfaces and water include hydroxylation of the phenyl groups, oxidation of the carbinol carbon atom, dehalogenation and carbinol dehydroxylation (Scheme 1). The primary metabolic pathway of nuarimol in rats involves mainly aryl hydroxylation (Scheme 2).

Degradation

Nuarimol is stable to hydrolytic degradation when maintained in sterile buffered solutions (pH 3,6 and 9) in the dark at 52 °C (Saunders, 1977). It was readily degraded in distilled water via photolysis. The photolytic DT50 of nuarimol was approximately 1 hour. Numerous photoproducts were observed; however, no structural characterisation information was reported (Zornes and Donoho, 1978).
Nuarimol was extensively photodegraded on solid surfaces. More than 80 photodegradation products were observed when nuarimol was exposed to sunlight on a stainless steel surface for up to 150 hours (Althaus, 1980a). All photoproducts were formed at very low levels (less than 3% each). The structures of 23 photoproducts were identified. An abbreviated photodegradation pathway of nuarimol (based on products accounting for 1% or greater) is presented in Scheme 1. These products were generated from the following reactions: aryl hydroxylation of the chlorophenyl and fluorophenyl moieties (to yield 2, 3), cleavage of the pyrimidine ring and the oxidation of the carbinol carbon atom (4,5) and dehydroxylation of the carbinol moiety (6). Carboxylic acid fragments from the phenyl(7,8,9) and pyrimidine moieties (10), resulting from the cleavage of the parent phenyl and pyrimidine linkages, were also observed.

NUARIMOL Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from NUARIMOL manufacturers

Career Henan Chemical Co
Product
NUARIMOL 63284-71-9
Price
US $1.00/KG
Min. Order
1KG
Purity
85.0-99.8%
Supply Ability
200kgs
Release date
2020-01-10

63284-71-9, NUARIMOLRelated Search:


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  • 63284-71-9
  • C17H12ClFN2O
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  • N-PAlphabetic
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  • Pyrimidines