ChemicalBook > CAS DataBase List > 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE
5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE
- Product Name
- 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE
- CAS No.
- 158848-32-9
- Chemical Name
- 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE
- Synonyms
- GR 159897;5-Fluoro-3-[2-[4-methoxy-4-[[-phenylsulphinyl]methyl]-1-piperidinyl]ethyl]-1H-indole;(R)-5-Fluoro-3-[2-[4-methoxy-4-[(phenylsulfinyl)methyl]-1-piperidinyl]ethyl]-1H-indole;5-Fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulfinyl]methyl]-1-piperidinyl]ethyl]-1H-indole;5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE;1H-Indole, 5-fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulfinyl]methyl]-1-piperidinyl]ethyl]-
- CBNumber
- CB3376531
- Molecular Formula
- C23H27FN2O2S
- Formula Weight
- 414.54
- MOL File
- 158848-32-9.mol
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5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Property
- Boiling point:
- 600.2±55.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO: ~24 mg/mL, soluble
- form
- solid
- pka
- 16.46±0.30(Predicted)
- color
- off-white
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Tocris
- Product number
- 1274
- Product name
- GR159897
- Purity
- ≥97%(HPLC)
- Packaging
- 10
- Price
- $224
- Updated
- 2021/12/16
Tocris
- Product number
- 1274
- Product name
- GR159897
- Purity
- ≥97%(HPLC)
- Packaging
- 50
- Price
- $915
- Updated
- 2021/12/16
TRC
- Product number
- G779510
- Product name
- GR159897
- Packaging
- 25mg
- Price
- $950
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- KIN0000295
- Product name
- 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $1327.97
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FF101805
- Product name
- GR 159897
- Packaging
- 5mg
- Price
- $250
- Updated
- 2021/12/16
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5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Chemical Properties,Usage,Production
Uses
GR 159897 is an NK2 receptor antagonist which aids in the treatment of IBS.
Biological Activity
A potent, selective, non-peptide, orally active neurokinin NK 2 receptor antagonist. Competes for binding of [ 3 H]GR100679 to hNK 2 -transfected CHO cells with a pK i of 9.5. Inhibits NK 2 receptor-mediated contraction of guinea pig trachea with a pA 2 of 8.7. Anxiolytic in vivo .
storage
Desiccate at -20°C
5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
158848-32-9, 5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLERelated Search:
5-FLUORO-N,N-DIMETHYLTRYPTAMINE
5-FLUORO-3-[2-[4-METHOXY-4-[[(R)-PHENYLSULPHINYL]METHYL]-1-PIPERIDINYL]ETHYL]-1H-INDOLE