ChemicalBook > CAS DataBase List > (R)-Tomoxetine

(R)-Tomoxetine

Product Name: (R)-Tomoxetine
CAS No.: 83015-26-3
Chemical Name: (R)-Tomoxetine
Synonyms: Tomoxetine;HSDB7352;HSDB 7352;HSDB-7352;TomoxetineHcl;(r)-tomoxetine;(R)-Atomoxetine;(R)-Tomoxetine USP/EP/BP;Atomoxetine impurity B CRS;Enantiomer of atomoxetine hydrochloride
CBNumber: CB3378328
Molecular Formula: C17H21NO
Formula Weight: 255.36
MOL File: 83015-26-3.mol

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(R)-Tomoxetine Property

Boiling point:: 389.0±37.0 °C(Predicted)
Density: 1.023±0.06 g/cm3(Predicted)
pka: 10.15±0.10(Predicted)
CAS DataBase Reference: 83015-26-3(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
Hazardous Substances Data: 83015-26-3(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H318Causes serious eye damage

H331Toxic if inhaled

H361Suspected of damaging fertility or the unborn child

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P310Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22248
Product name: Atomoxetine
Purity: ≥98%
Packaging: 5mg
Price: $55
Updated: 2021/12/16

Cayman Chemical

Product number: 22248
Product name: Atomoxetine
Purity: ≥98%
Packaging: 10mg
Price: $99
Updated: 2021/12/16

Cayman Chemical

Product number: 22248
Product name: Atomoxetine
Purity: ≥98%
Packaging: 25mg
Price: $220
Updated: 2021/12/16

Cayman Chemical

Product number: 22248
Product name: Atomoxetine
Purity: ≥98%
Packaging: 50mg
Price: $330
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004702
Product name: ATOMOXETINE
Purity: 95.00%
Packaging: 100MG
Price: $525
Updated: 2021/12/16

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(R)-Tomoxetine Chemical Properties,Usage,Production

Uses

(R)-Tomoxetine is a compound active at novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases.

Definition

(R)-Tomoxetine is a secondary amino compound having methyl and 3-(2-methylphenoxy)-3-phenylpropan-1-yl substituents.

brand name

Strattera (Lilly).

in vivo

Atomoxetine (Tomoxetine) (0.3-3 mg/kg; i.p.; 0-4 hours; male Sprague-Dawley rats) increases extracellular norepinephrine and dopamine by 3-fold and increases Fos expression in the rat prefrontal cortex^[1].
Atomoxetine (Tomoxetine) (0.1-5 mg/kg; i.p. and p.o; for 14 days; spontaneously hypertensive rat) can improve behaviors associated with ADHD in rats^[3].

Animal Model:	Male Sprague-Dawley rats^[1]
Dosage:	0.3, 1 and 3 mg/kg
Administration:	Intraperitoneal injection; for 4 hours
Result:	Increased the number of cells expressing Fos-like immunoreactivity in PFC 3.7-fold and increased extracellular norepinephrine and dopamine by 3-fold.

Animal Model:	Spontaneously hypertensive rat (SHR)^[3]
Dosage:	0.1, 0.3, 1.25 and 5.0 mg/kg
Administration:	Intraperitoneal injection and oral administration; for 14 days
Result:	Had non-impact on the measurement of motor activity.

(R)-Tomoxetine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (R)-Tomoxetine manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: (R)-N-methyl-3-(2-methyl phenoxy)benzenepropanamine 83015-26-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

Career Henan Chemical Co

Product: (R)-Tomoxetine 83015-26-3
Price: US $2.00/KG
Min. Order: 1g
Purity: 98%MIN
Supply Ability: ASK
Release date: 2020-01-07

83015-26-3, (R)-TomoxetineRelated Search:

METSULFURON METHYL Methanol Tribenuron methyl Basic Violet 1 Methylparaben Moxifloxacin Methyl acrylate Methyl salicylate Kresoxim-methyl Methyl Atomoxetine impurity Atomoxetine Related Compound C (10 mg) (N-methyl-3-phenyl-3-(p-tolyloxy)propan-1-amine hydrochloride) Atomoxetine Impurity 15 4’-Hydroxy Atomoxetine -D-Glucuronide 3-(N-Benzyl-N-methylamino)propiophenone hydrochloride INDEX NAME NOT YET ASSIGNED Atomoxetine impurity D (E)-N-Methyl-3-phenyl-2-propen-1-aMine

n-methyl-3-(2-methylphenoxy)benzenepropanamine

(r)-tomoxetine

Tomoxetine

TomoxetineHcl

N-Methyl--(2-methylphenoxy)benzenepropanamine

N-Methyl-3-(2-methylphenoxy)-3-phenylpropylamine

(R)-N-Methyl-3-phenyl-3-(2-methylphenoxy)-1-propanamine

Methyl[(R)-3-phenyl-3-(2-methylphenoxy)propyl]amine

(-)-N-Methyl-3-(o-methylphenoxy)-3-phenylpropylamine

BenzenepropanaMine, N-Methyl-g-(2-Methylphenoxy)-, (R)-

(R)-Atomoxetine

BenzenepropanaMine,N-Methyl-gaMMa-(2-Methylphenoxy)-, (gaMMaR)-

(R)-N-methyl-3-(2-methylphenoxy)benzenepropanamine

(3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine

(R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine

Atomoxetine for impurity A identification CRS

Atomoxetine impurity B CRS

Benzenepropanamine, N-methyl-γ-(2-methylphenoxy)-, (γR)-

(R)-Tomoxetine USP/EP/BP

Enantiomer of atomoxetine hydrochloride

HSDB 7352

HSDB7352

HSDB-7352

83015-26-3

Inhibitors

Pharmacetes & Fine Chemicalsuticals