(S)-(+)-NOREPINEPHRINE L-BITARTRATE

Product Name: (S)-(+)-NOREPINEPHRINE L-BITARTRATE
CAS No.: 636-88-4
Chemical Name: (S)-(+)-NOREPINEPHRINE L-BITARTRATE
Synonyms: Imidacloprid Impurity 29;(+)-Noradrenaline Bitartrate;D-(+)-Noradrenaline Tartrate;(S)-(+)-NOREPINEPHRINE L-BITARTRATE;Norepinephrine tartrate impurity 33;D-Norepinephrine hydrogen tartrate salt;D-Noradrenaline (Norepinephrine) Bitartrate;4-[(1S)-2-amino-1-hydroxy-ethyl]pyrocatechol;(S)-4-(2-amino-1-hydroxyethyl)benzene-1,2-diol;4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol
CBNumber: CB3388503
Molecular Formula: C12H17NO9
Formula Weight: 319.27
MOL File: 636-88-4.mol

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(S)-(+)-NOREPINEPHRINE L-BITARTRATE Property

Melting point:: 166 °C (dec.)(lit.)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly, Sonicated)
form: Solid
color: White to Off-White
optical activity: [α]20/D +38°, c = 1 in H2O
Stability:: Hygroscopic
InChI: InChI=1/C8H11NO3.C4H6O6/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10)/t8-;1-,2-/s3
InChIKey: WNPNNLQNNJQYFA-KBOIKTAVNA-N
SMILES: [C@H](O)(C(=O)O)[C@@H](O)C(=O)O.[C@@H](C1C=CC(O)=C(O)C=1)(O)CN |&1:0,5,10,r|

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Safety

Hazard Codes: T,Xn
Risk Statements: 25-36/37/38-20/21/22
Safety Statements: 36/37-45-37/39-26
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
F: 8-10-23

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed
Precautionary statements: P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 407453
Product name: (S)-(+)-Norepinephrine L-bitartrate
Purity: 99%
Packaging: 1g
Price: $1160
Updated: 2022/05/15

TRC

Product number: N661025
Product name: (+)-NoradrenalineBitartrate
Packaging: 10mg
Price: $180
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA146097
Product name: 4-[(1S)-2-Amino-1-Hydroxy-Ethyl]Benzene-1,2-Diol
Packaging: 50mg
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA146097
Product name: 4-[(1S)-2-Amino-1-Hydroxy-Ethyl]Benzene-1,2-Diol
Packaging: 100mg
Price: $105
Updated: 2021/12/16

Matrix Scientific

Product number: 096279
Product name: (S)-(+)-Norepinephrine L-bitartrate
Purity: 95+%
Packaging: 250mg
Price: $189
Updated: 2021/12/16

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(S)-(+)-NOREPINEPHRINE L-BITARTRATE Chemical Properties,Usage,Production

Uses

(+)-Noradrenaline Bitartrate is an agonist at a1- and a2-adrenoreceptors.

Purification Methods

Recrystallise adrenor from EtOH and store it in the dark under N2. [pKa, Lewis Brit J Pharmacol Chemother 9 488 1954, UV: Bergstr.m et al. Acta Physiol Scand 20 101 1950, Fluorescence: Bowman et al. Science NY 122 32 1955, Tullar J Am Chem Soc 70 2067 1948.] The L-tartrate salt monohydrate has m 102-104.5o, [] D -11o (c 1.6, H2O), after recrystallisation from H2O or EtOH. [Beilstein 13 III 2382.]

(S)-(+)-NOREPINEPHRINE L-BITARTRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-(+)-NOREPINEPHRINE L-BITARTRATE Suppliers

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636-88-4, (S)-(+)-NOREPINEPHRINE L-BITARTRATERelated Search:

Isoproterenol Aminophylline Norepinephrine 3,4-DIHYDROXYBENZYL ALCOHOL

ALPHA-(AMINOMETHYL)-3,4-DIHYDROXYBENZYL ALCOHOL L-BITARTRATE

(S)-(+)-NOREPINEPHRINE L-BITARTRATE

D-Norepinephrine hydrogen tartrate salt

(S)-beta,3,4-trihydroxyphenethylammonium [R-(R*,R*)]-hydrogen tartrate

D-Noradrenaline L-bitartrate, D-Noradrenaline hydrogen L-tartrate, D-Norepinephrine D-bitartrate, (+)-α-(Aminomethyl)-3,4-dihydroxybenzyl alcohol (+)-tartrate (1:1)

D-Arterenol hydrogen tartrate salt, D-Noradrenaline hydrogen tartrate salt, D-Norepinephrine bitartrate

4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol

4-[(1S)-2-amino-1-hydroxy-ethyl]pyrocatechol

4-[(1S)-2-azanyl-1-hydroxy-ethyl]benzene-1,2-diol

(S)-4-(2-amino-1-hydroxyethyl)benzene-1,2-diol(2R,3R)-2,3-dihydroxysuccinate

(+)-Noradrenaline Bitartrate

D-Noradrenaline (Norepinephrine) Bitartrate

(S)-4-(2-amino-1-hydroxyethyl)benzene-1,2-diol

Epinephrine Impurity 2 Tartrate(D-Norepinephrine Bitartrate)

Imidacloprid Impurity 29

Epinephrine Impurity 13 2 Tartrate(D-Norepinephrine

D-(+)-Noradrenaline Tartrate

Norepinephrine tartrate impurity 33

636-88-4

HO2C6H3CHCH2NH2OHC4H6O6

C12H17O9N

Organic Building Blocks

Amino Alcohols

Chiral Building Blocks

Asymmetric Synthesis