ChemicalBook > CAS DataBase List > N-TRICOSANOYLTRYPTAMINE

N-TRICOSANOYLTRYPTAMINE

Product Name: N-TRICOSANOYLTRYPTAMINE
CAS No.: 697226-52-1
Chemical Name: N-TRICOSANOYLTRYPTAMINE
Synonyms: TAT;MEC17;BR2-SH;TAT-amide;ATAT1 human;TAT(47-57)-amide;N-TRICOSANOYLTRYPTAMINE;Tyrosine aminotransferase;TRICOSANOIC ACID TRYPTAMIDE;alpha tubulin acetyltransferase 1
CBNumber: CB3388927
Molecular Formula: C64H119N33O13
Formula Weight: 1558.84
MOL File: Mol file

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N-TRICOSANOYLTRYPTAMINE Property

Melting point:: 116-120 °C
Density: 1.54±0.1 g/cm3(Predicted)
storage temp.: -20°C
form: Solid
color: White to off-white
biological source: rabbit
Sequence: Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2

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Safety

WGK Germany: 3
F: 10

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SRP0309
Product name: ATAT1 human
Purity: recombinant, expressed in <I>E. coli</I>, ≥55% (SDS-PAGE)
Packaging: 50 μg
Price: $691
Updated: 2025/07/31

Sigma-Aldrich

Product number: SAB1303103
Product name: ANTI-TAT (CENTER) antibody produced in rabbit
Purity: IgG fraction of antiserum, buffered aqueous solution
Packaging: 400μL
Price: $496
Updated: 2025/07/31

Sigma-Aldrich

Product number: SAB1303103
Product name: ANTI-TAT (CENTER) antibody produced in rabbit
Purity: IgG fraction of antiserum, buffered aqueous solution
Packaging: 100μG
Price: $423
Updated: 2022/05/15

Usbiological

Product number: 493419
Product name: TAT
Packaging: 100ul
Price: $499
Updated: 2021/12/16

Usbiological

Product number: 359141
Product name: TAT
Packaging: 48Tests
Price: $588
Updated: 2021/12/16

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N-TRICOSANOYLTRYPTAMINE Chemical Properties,Usage,Production

Uses

TAT-amide is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells[1][2].

Biological Activity

ATAT1 (α tubulin acetyltransferase 1) catalyses the acetylation of lysine 40 of α-tubulin and microtubule. ATAT1 expression is essential for microtubule stabilization and mediates cilium formation. Upart from acetylation, αTAT1 interacts with doublecortin (a microtubule associated protein) to degrade microtubules th at are not aligned with acetyltransferase activity. αTAT1 regulates the Wnt1 signalling pathway via β-catenin and promotes tumorigenesis. Overexpression of the ATAT1 gene is observed in colon cancer and is known to contribute to its progression.

References

[1] Xu P, et al. Precise control of apoptosis via gold nanostars for dose dependent photothermal therapy of melanoma. J Mater Chem B. 2019 Nov 28;7(44):6934-6944. DOI:10.1039/c9tb01956a
[2] Okuda-Shinagawa NM, et al. Fluorescent and Photosensitizing Conjugates of Cell-Penetrating Peptide TAT(47-57): Design, Microwave-Assisted Synthesis at 60 °C, and Properties. ACS Omega. 2017 Nov 30;2(11):8156-8166. DOI:10.1021/acsomega.7b01127

N-TRICOSANOYLTRYPTAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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697226-52-1, N-TRICOSANOYLTRYPTAMINERelated Search:

TYR-MET-GLU-HIS-PHE-ARG-TRP H-TYR-LYS-GLY-ARG-CYCLO(-GLU-TYR-ILE-LYS)-LEU-ILE-THR-ARG-PRO-ARG-TYR-NH2 TYR-CORTICOTROPIN RELEASING FACTOR HUMAN, RAT TYR-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG TYR-ACTH (4-10) H-TYR-SER-GLN-GLU-PRO-PRO-ILE-SER-LEU-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-VAL-LEU-GLU-MET-THR-LYS-ALA-ASP-GLN-LEU-ALA-GLN-GLN-ALA-HIS-SER-ASN-ARG-LYS-LEU-LEU-ASP-ILE-ALA-NH2 TYR-LEPTIN (26-39) (HUMAN) TAT-Gap19 TAT 2-4 TAT-cyclo-CLLFVY TAT peptide L(+)-Arginine TRICOSANOIC ACID IL-18 Human P GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-LYS-ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU L-Arginine, L-α-aspartyl-L-seryl-L-leucyl-L-lysyl-L-seryl-L-tyrosyl-L-tryptophyl-L-tyrosyl-L-leucyl-L-glutaminyl-L-lysyl-L-phenylalanyl-L-seryl-L-tryptophyl- H-Ala-Cys-Ser-Ser-Ser-Pro-Ser-Lys-His-Cys-Gly-OH, (Disulfide bond)

H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2

TAT

N-TRICOSANOYLTRYPTAMINE

N-[2-(3-INDOLYL)ETHYL]TRICOSANAMIDE

TRICOSANOIC ACID TRYPTAMIDE

TYR-GLY-ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-ARG-NH2

alpha tubulin acetyltransferase 1

ATAT1 human

MEC17

ANTI-TAT (CENTER) antibody produced in rabbit

L-tyrosine:2-oxoglutarate aminotransferase

Tyrosine aminotransferase

TAT-amide

BR2-SH

L-Argininamide, L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-

Hiv-1 tat protein (47-57) amide trifluoroacetate salt

TAT(47-57)-amide

697226-52-1

C64H119N33O13

Peptide