GLP-2 (HUMAN) TRIFLUOROACETATE SALT
- Product Name
- GLP-2 (HUMAN) TRIFLUOROACETATE SALT
- Chemical Name
- GLP-2 (HUMAN) TRIFLUOROACETATE SALT
- Synonyms
- GLP-2 (HUMAN) TRIFLUOROACETATE SALT;PROGLUCAGON (126-158) (HUMAN) TRIFLUOROACETATE SALT;GLUCAGON-LIKE PEPTIDE 2 (HUMAN) TRIFLUOROACETATE SALT;PREPROGLUCAGON (146-178) (HUMAN) TRIFLUOROACETATE SALT
- CBNumber
- CB3396193
- Molecular Formula
- C173H267F3N48O58S
- Formula Weight
- 4036.32
- MOL File
- Mol file
GLP-2 (HUMAN) TRIFLUOROACETATE SALT Property
- storage temp.
- -15°C
- solubility
- Formic Acid: 1 mg/ml
N-Bromosuccinimide Price
- Product number
- 24414
- Product name
- GLP-2 (human) (trifluoroacetate salt)
- Packaging
- 1mg
- Price
- $323
- Updated
- 2024/03/01
GLP-2 (HUMAN) TRIFLUOROACETATE SALT Chemical Properties,Usage,Production
Description
Glucagon-like peptide-2 (GLP-2) is an endogenous peptide hormone formed in L cells of the small and large intestine by cleavage of proglucagon in response to nutrient ingestion. In vivo, GLP-2 (43.75 μg twice a day) increases crypt cell proliferation, total weight of the small bowel, and mucosal thickness of the proximal and distal jejunum and ileum in mice. It increases jejunal mucosal surface area and reduces resection-induced decreases in SGLT-1 and GLUT-2 transporter abundance, as well as resection-induced increases in blood glucose levels and body fat loss, in a rat model of distal bowel resection. GLP-2 also increases intrahepatic lipid concentration, hepatic steatosis, and plasma concentrations of cholesterol and triglycerides in mice fed a high-fat diet but has no effect on mice fed a standard diet.
References
[1] D J DRUCKER. Induction of intestinal epithelial proliferation by glucagon-like peptide 2.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1996, 93 15: 7911-7916. DOI: 10.1073/pnas.93.15.7911
[2] S. BALDASSANO. Influence of endogenous glucagon-like peptide-2 on lipid disorders in mice fed a high-fat diet[J]. Endocrine Research, 2016, 41 1: 317-324. DOI: 10.3109/07435800.2016.1141950
[3] SARAH W LAI. Effects of exogenous glucagon-like peptide-2 and distal bowel resection on intestinal and systemic adaptive responses in rats.[J]. PLoS ONE, 2017: e0181453. DOI: 10.1371/journal.pone.0181453
GLP-2 (HUMAN) TRIFLUOROACETATE SALT Preparation Products And Raw materials
Raw materials
Preparation Products
GLP-2 (HUMAN) TRIFLUOROACETATE SALT Suppliers
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