PYRAZOPHOS Property

Melting point:

51℃

Density 

1.38±0.1 g/cm3(Predicted)

vapor pressure 

2.2 x 10^-4 Pa (50 °C)

storage temp. 

APPROX 4°C

pka

-1.37±0.40(Predicted)

Water Solubility 

4.2 mg l^-1 (25 °C)

Merck 

13,8052

BRN 

577209

EPA Substance Registry System

Pyrazophos (13457-18-6)

Safety

Hazard Codes 

Xn,N

Risk Statements 

20/22-50/53

Safety Statements 

36/37-46-60-61

RIDADR 

2783

WGK Germany 

3

RTECS 

TF2035000

HazardClass 

6.1(b)

PackingGroup 

III

Toxicity

LD50 in rats, marmots, rabbits (mg/kg): 140, 184, 435 orally (Smit)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H332Harmful if inhaled

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

PYRAZOPHOS Chemical Properties,Usage,Production

Uses

Pyrazophos is a systemic fungicide that provides both protective and curative control of various fungal diseases such as powdery mildew (Podosphaera) on apples, stone fruits, bush fruits and strawberries, Erysiphe in cucurbits and tomatoes, Uncinula on vines and leaf blotch (Rhynchosporium) in cereals.

Uses

Pyrazophos is an anticholinesterase pesticide used on fruits and vegetables and can be determined by gas chromatography/mass spectrometry and liquid chromatography with fluorescence detection.

Uses

Fungicide.

Definition

ChEBI: A member of the class of pyrazolopyrimidines that is the ethyl ester of 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid. A fungicide used to control Erysiphe, Helminthosporium and ital>Rhynchospium in cereals.

Metabolic pathway

Limited information is available to describe the degradation and metabolic fate of pyrazophos. Hydrolytic cleavage of the P-O-pyrazolopyrimidine linkage is the primary metabolic pathway. Oxidative desulfuration of pyrazophos to pyrazophos-oxon is only a minor pathway, observed in the plant metabolism study (Scheme 1).

Metabolism

Its mode of action is believed to be the inhibition of melanin biosynthesis and the development of appressoria by fungal conidia. Formulation is available as emulsifiable concentrate (EC: 30%). Application rates on Oidium spp. are in the range of 15–30 g a.i./hl.

Degradation

Pyrazophos (1) is hydrolysed in acidic or alkaline solution (PM).