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BNP-32 (RAT)

Product Name
BNP-32 (RAT)
CAS No.
133448-20-1
Chemical Name
BNP-32 (RAT)
Synonyms
BNP RAT;BNP-32 (RAT);BNP (1-32) RAT;BNP (51-95), RAT;BNP-32 (rat) trifluoroacetate;NSKMAHSSSCFGQKIDRIGAVSRLGCDGLRLF;Brain Natriuretic Peptide (1-32);BRAIN NATRIURETIC PEPTIDE-32 (RAT);Rat brain natriuretic peptide(1-32);BRAIN NATRIURETIC PEPTIDE (1-32), RAT
CBNumber
CB3403598
Molecular Formula
C146H239N47O44S3
Formula Weight
3452.94
MOL File
133448-20-1.mol
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BNP-32 (RAT) Property

Density 
1.50±0.1 g/cm3(Predicted)
storage temp. 
-20°C
form 
powder
Water Solubility 
Soluble in Water
Sequence
Asn-Ser-Lys-Met-Ala-His-Ser-Ser-Ser-Cys-Phe-Gly-Gln-Lys-Ile-Asp-Arg-Ile-Gly-Ala-Val-Ser-Arg-Leu-Gly-Cys-Asp-Gly-Leu-Arg-Leu-Phe (Disulfide bridge: Cys10-Cys26)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FB109674
Product name
BNP-32 (rat) trifluoroacetate
Packaging
500ug
Price
$550
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0003941
Product name
BNP (1-32), RAT
Purity
95.00%
Packaging
0.5MG
Price
$950
Updated
2021/12/16
ChemScene
Product number
CS-0044640
Product name
Brain Natriuretic Peptide (1-32), rat
Packaging
5mg
Price
$1100
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0003941
Product name
BNP (1-32), RAT
Purity
95.00%
Packaging
1MG
Price
$1360
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0003941
Product name
BNP (1-32), RAT
Purity
95.00%
Packaging
2.5MG
Price
$2800
Updated
2021/12/16
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BNP-32 (RAT) Chemical Properties,Usage,Production

Uses

Brain Natriuretic Peptide (1-32), rat (BNP (1-32), rat) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes)[1].

Biochem/physiol Actions

Brain natriuretic peptide (type B natriuretic peptide) was originally isolated from brain, but is mainly produced in myoendocrine cells of the heart ventricles from which it is released into the circulation. It is involved in blood pressure control and cardiovascular homeostasis.

in vivo

The depressor, natriuretic and cyclic GMP responses to several species of brain natriuretic peptide (BNP) are compared to atrial natriureticpeptide (ANP) 99-126 in conscious spontaneously hypertensive rats (SHR) and in conscious cynomolgus monkeys treated with vehicle or the selective neutral endopeptidase inhibitor SQ 28603. In the conscious SHR, the natriuretic and cyclic GMP responses to 3 nmol/kg i.v. rat BNP (1-32) greater than rat ANP 99-126 greater than pig BNP-26 and sre significantly potentiated by 100 mumol/kg i.v. SQ 28,603. Human BNP-32 is inactive in the SHR treated with either vehicle or SQ 28,603. In contrast, 1 nmol/kg i.v. of human BNP (1-32) stimulates renal and depressor responses in the conscious monkeys that are greater than or equal to those elicited by human ANP 99-126, whereas 3 nmol/kg i.v. rat BNP (1-32) reduces mean arterial pressure without affecting renal function[3].

References

[1] Dickey DM, et al. Human B-type natriuretic peptide is not degraded by meprin A. Biochem Pharmacol. 2010 Oct 1;80(7):1007-11. DOI:10.1016/j.bcp.2010.06.015
[2] Wellard J, et al. Natriuretic peptides, but not nitric oxide donors, elevate levels of cytosolic guanosine 3',5'-cyclic monophosphate in ependymal cells ex vivo. Neurosci Lett. 2006 Jan 16;392(3):187-92. DOI:10.1016/j.neulet.2005.09.084
[3] Seymour AA, et al. Potentiation of brain natriuretic peptides by SQ 28,603, an inhibitor of neutral endopeptidase3.4.24.11, in monkeys and rats. J Pharmacol Exp Ther. 1992 Jul;262(1):60-70. PMID:1385630

BNP-32 (RAT) Preparation Products And Raw materials

Raw materials

Preparation Products

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BNP-32 (RAT) Suppliers

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Fax
0551-65326641
Email
info@cellmano.com
Country
China
ProdList
1010
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6083
Advantage
56
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
6687
Advantage
55
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58

133448-20-1, BNP-32 (RAT)Related Search:


  • H-ASN-SER-LYS-MET-ALA-HIS-SER-SER-SER-CYS-PHE-GLY-GLN-LYS-ILE-ASP-ARG-ILE-GLY-ALA-VAL-SER-ARG-LEU-GLY-CYS-ASP-GLY-LEU-ARG-LEU-PHE-OH
  • H-ASN-SER-LYS-MET-ALA-HIS-SER-SER-SER-CYS-PHE-GLY-GLN-LYS-ILE-ASP-ARG-ILE-GLY-ALA-VAL-SER-ARG-LEU-GLY-CYS-ASP-GLY-LEU-ARG-LEU-PHE-OH (DISULFIDE BRIDGE: 10-26)
  • H-ASN-SER-LYS-MET-ALA-HIS-SER-SER-SER-CYS-PHE-GLY-GLN-LYS-ILE-ASP-ARG-ILE-GLY-ALA-VAL-SER-ARG-LEU-GLY-CYS-ASP-GLY-LEU-ARG-LEU-PHE-OH, (DISULFIDE BOND)
  • B-TYPE (BRAIN) NATRIURETIC PEPTIDE-32 (RAT)
  • BRAIN NATRIURETIC PEPTIDE-32 (RAT)
  • BRAIN NATRIURETIC PEPTIDE (1-32), RAT
  • BNP (1-32) RAT
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  • BNP-32 (RAT)
  • ASN-SER-LYS-MET-ALA-HIS-SER-SER-SER-CYS-PHE-GLY-GLN-LYS-ILE-ASP-ARG-ILE-GLY-ALA-VAL-SER-ARG-LEU-GLY-CYS-ASP-GLY-LEU-ARG-LEU-PHE
  • NSKMAHSSSCFGQKIDRIGAVSRLGCDGLRLF
  • NSKMAHSSSCFGQKIDRIGAVSRLGCDGLRLF (DISULFIDE BRIDGE: 10-26)
  • 14-45-Brain natriuretic peptide-45 (rat)
  • Rat brain natriuretic peptide(1-32)
  • L-Asn-L-Ser-L-Lys-L-Met-L-Ala-L-His-L-Ser-L-Ser-L-Ser-L-Cys(1)-L-Phe-Gly-L-Gln-L-Lys-L-Ile-L-Asp-L-Arg-L-Ile-Gly-L-Ala-L-Val-L-Ser-L-Arg-L-Leu-Gly-L-Cys(1)-L-Asp-Gly-L-Leu-L-Arg-L-Leu-L-Phe-OH
  • ASN-SER-LYS-MET-ALA-HIS-SER-SER-SER-CYS-PHE-GLY-GLN-LYS-ILE-ASP-ARG-ILE-GLY-ALA-VAL-SER-ARG-LEU-GLY-CYS-ASP- GLY-LEU-ARG-LEU-PHE(DISULFIDE BRIDGE:CYS10-CYS26)
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  • Brain Natriuretic Peptide (BNP) (1-32), rat
  • Brain natriuretic peptide-32 rat, ≥97% (HPLC)
  • 14-45-Brain natriuretic peptide-45 (rat) (9CI)
  • Brain Natriuretic Peptide-32 rat >=97% (HPLC), powder
  • Brain Natriuretic Peptide (1-32)
  • ASN-SER-LYS-MET-ALA-HIS-SER-SER-SER-CYS-PHE-GLY-GLN-LYS-ILE-ASP-ARG-ILE-GLY-ALA-VAL-SER-ARG-LEU-GLY-CYS-ASP-GLY-LEU-ARG-LEU-PHE
  • 133448-20-1
  • C146H239N47O44S3
  • BioChemical
  • Amino Acids and Peptides
  • Biochemicals and Reagents
  • Natriuretic Peptides
  • Peptides
  • Peptide