1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE

Product Name: 1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE
CAS No.: 699-51-4
Chemical Name: 1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE
Synonyms: ba2839;NSC 1024;5,5-TETRAMETHYLENEHYDANTOIN;Hydantoin-5-spirocyclopentane;5,5’-cyclopentanespirohydantoin;5,5-tetramethylenespirohydantoin;Spiro[cyclopentane-1,5'-hydantoin];1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE;1,3-diazaspiro[4.4]nonane-2,4-quinone
CBNumber: CB3405527
Molecular Formula: C7H10N2O2
Formula Weight: 154.17
MOL File: 699-51-4.mol

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1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE Property

Melting point:: 204-205℃
Density: 1.31
storage temp.: 2-8°C
solubility: DMSO: 2 mg/mL, clear
form: powder
pka: 10.46±0.20(Predicted)
color: white to beige
Appearance: White to off-white Solid
InChI: InChI=1S/C7H10N2O2/c10-5-7(3-1-2-4-7)9-6(11)8-5/h1-4H2,(H2,8,9,10,11)
InChIKey: JTTFXYHJDZZDQK-UHFFFAOYSA-N
SMILES: N1C2(CCCC2)C(=O)NC1=O

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S355909
Product name: 5,5-TETRAMETHYLENEHYDANTOIN
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $185
Updated: 2025/07/31

Sigma-Aldrich

Product number: S355909
Product name: 5,5-TETRAMETHYLENEHYDANTOIN
Purity: Aldrich
Packaging: 1g
Price: $179
Updated: 2024/03/01

TRC

Product number: D422628
Product name: 1,3-Diazaspiro[4.4]nonane-2,4-dione
Packaging: 50mg
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 135738
Product name: 1,3-Diazaspiro[4.4]nonane-2,4-dione
Purity: 95%+
Packaging: 1g
Price: $101
Updated: 2021/12/16

Apolloscientific

Product number: OR965025
Product name: 1,3-Diazaspiro[4.4]nonane-2,4-dione
Purity: 95%
Packaging: 1g
Price: $115
Updated: 2021/12/16

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1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE Chemical Properties,Usage,Production

Uses

Non-toxic spiro-hydantoin, reverses plant vernalization epigenetically by reducing H3K27me3 at FLC, enabling heat-free control over flowering time.
DVR06, identified in Arabidopsis thaliana, induces devernalization, reversing the vernalized state at ambient temperatures. Its core function is reactivating the floral repressor FLC within the nucleus, notably in vascular and meristematic tissues. Mechanistically, DVR06 reduces repressive H3K27me3 histone methylation at the FLC locus and other genomic sites, while leaving active H3K4me3 marks unchanged. This epigenetic modulation delays flowering time and enhances vegetative growth. Possessing low toxicity and key hydantoin/spiro pharmacophores, DVR06 serves as a valuable chemical probe for epigenetic memory and holds potential for agricultural control over plant life cycles.

1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE Suppliers

China 53 Germany 1 India 2 Switzerland 1 Ukraine 2 United Kingdom 2 United States 13 Global 74

Shanghai Jinsheng Pharmaceutical Co., Ltd.

Tel: 1365-13651960330 13651960330
Email: xiangfeixia@jspharmatech.com
Country: China
ProdList: 373
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
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Advantage: 64

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25700
Advantage: 65

Shanghai Sheepchem Co., Ltd.

Tel: +86 (21) 6715-7650
Fax: +86 (21) 6715-7651
Email: sheepchem@163.com
Country: China
ProdList: 994
Advantage: 60

Anichem Inc.

Tel: 0512-69369885
Fax: 0512-69369880
Email: sales@anichem.com.cn
Country: China
ProdList: 495
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Shanghai Hong-chuang Pharma Tech Co., Ltd.

Tel: 18151128828
Fax: -
Email: hc-sales@foxmail.com
Country: China
ProdList: 2648
Advantage: 55

Porse Fine Chemical Co.,LTD

Tel: 20-66003216 18666003216
Fax: +86-20-28069063
Email: info@porsefinechemical.com
Country: China
ProdList: 1941
Advantage: 62

Accela ChemBio Inc.

Tel: +1(858) 699-3322
Fax: +1(858) 876-1948
Email: marketing@accelachem.com
Country: United States
ProdList: 6024
Advantage: 65

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ChengDu TongChuangYuan Pharmaceutical Co.Ltd

Tel: 028-83379370 13880556291
Fax: 028-87747383
Email: tcy@tcypharm.com
Country: China
ProdList: 7220
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View Lastest Price from 1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE manufacturers

Henan Fengda Chemical Co., Ltd

Product: 1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE 699-51-4
Price: US $3.00-0.20/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-26

Career Henan Chemical Co

Product: 1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE 699-51-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2018-08-15

699-51-4, 1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONERelated Search:

Spiriprostil 3-(2-aminoethyl)-1,3-diazaspiro[4.4]nonane-2,4-dione 3-(2,4-DIOXO-1,3-DIAZASPIRO[4.4]NON-3-YL)PROPANENITRILE 4-(2,4-DIOXO-1,3-DIAZA-SPIRO[4.4]NON-3-YL)-BUTYRIC ACID 3-(2,4-DIOXO-1,3-DIAZA-SPIRO[4.4]NON-3-YL)-PROPIONIC ACID 1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE 3-(2-amino-3,3-dimethylbutyl)-1,3-diazaspiro[4.4]nonane-2,4-dione 7,7-DIMETHYL-2',5'-DIOXO-1H-SPIRO[BICYCLO[2.2.1]HEPTANE-2,4'-IMIDAZOLIDINE]-1-CARBOXYLIC ACID cypenhymustine 2-(2,4-DIOXO-1,3-DIAZASPIRO[4.4]NON-3-YL)ETHANESULFONYL FLUORIDE 3-(3-amino-2-hydroxypropyl)-1,3-diazaspiro[4.4]nonane-2,4-dione 3-(3-chloropropyl)-1,3-diazaspiro[4.4]nonane-2,4-dione 3-AMINO-1,3-DIAZASPIRO[4.4]NONANE-2,4-DIONE (2,4-DIOXO-1,3-DIAZASPIRO[4.4]NON-3-YL)ACETIC ACID 1,7,7-TRIMETHYL-2',5'-DIOXO-4H-SPIRO[BICYCLO[2.2.1]HEPTANE-2,4'-IMIDAZOLIDINE]-4-CARBOXYLIC ACID

5,5’-cyclopentanespirohydantoin

5,5-tetramethylenespirohydantoin

ba2839

5,5-TETRAMETHYLENEHYDANTOIN

1,3-DIAZA-SPIRO[4.4]NONANE-2,4-DIONE

1,3-diazaspiro[4.4]nonane-2,4-quinone

Hydantoin-5-spirocyclopentane

NSC 1024

Spiro[cyclopentane-1,5'-hydantoin]

699-51-4