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ML298

Product Name
ML298
CAS No.
1426916-02-0
Chemical Name
ML298
Synonyms
ML298;CID53393915;ML298 >=98% (HPLC);ML-298,Inhibitor,ML 298,Phospholipase,inhibit;3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-benzamide;Benzamide, 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-
CBNumber
CB34199383
Molecular Formula
C22H23F3N4O2
Formula Weight
432.44
MOL File
1426916-02-0.mol
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ML298 Property

storage temp. 
2-8°C
solubility 
DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml
form 
powder
color 
white to beige
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1077
Product name
ML298
Purity
≥98% (HPLC)
Packaging
5MG
Price
$117
Updated
2023/06/20
Sigma-Aldrich
Product number
SML1077
Product name
ML298
Purity
≥98% (HPLC)
Packaging
25MG
Price
$371
Updated
2023/06/20
Cayman Chemical
Product number
15349
Product name
ML-298
Purity
≥98%
Packaging
1mg
Price
$40
Updated
2024/03/01
Cayman Chemical
Product number
15349
Product name
ML-298
Purity
≥98%
Packaging
5mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
15349
Product name
ML-298
Purity
≥98%
Packaging
10mg
Price
$195
Updated
2024/03/01
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ML298 Chemical Properties,Usage,Production

Description

ML-298 is an inhibitor of phospholipase D2 (PLD2; IC50 = 355 nM). It is selective for PLD2 over PLD1 (IC50 = 20,000 nM). It decreases invasive migration of U87-MG glioblastoma cells when used at a concentration of 10 μM without inducing cytotoxicity.

Uses

ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2).

Biochem/physiol Actions

ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2; IC50 = 355 nM). ML298 does not affect PLD1 activity at concentrations up to 20 μM.

ML298 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML298 Suppliers

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1426916-02-0, ML298Related Search:


  • ML298
  • Benzamide, 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-
  • ML298 >=98% (HPLC)
  • CID53393915
  • ML-298,Inhibitor,ML 298,Phospholipase,inhibit
  • 3,4-difluoro-N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-benzamide
  • 1426916-02-0