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H-THR(TBU)-OME HCL

Product Name
H-THR(TBU)-OME HCL
CAS No.
71989-43-0
Chemical Name
H-THR(TBU)-OME HCL
Synonyms
H-Thr(tBu);H-Thr(tBu)-OMe;Thr(OtBu)-Ome.HCl;L-Thr(tBu)-OMe·HCl;H-THR(TBU)-OME HCL;H-THR(BUT)-OME HCL;H-Thr(tBu)-Ome. HC;H-L-THR(TBU)-OME HCL;THREONINE(TBU)-OME HCL;H-THR(TBU)-OME HCL USP/EP/BP
CBNumber
CB3427653
Molecular Formula
C9H20ClNO3
Formula Weight
225.71
MOL File
71989-43-0.mol
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H-THR(TBU)-OME HCL Property

storage temp. 
Inert atmosphere,2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Solid
color 
White to off-white
BRN 
4716005
InChI
InChI=1/C9H19NO3.ClH/c1-6(13-9(2,3)4)7(10)8(11)12-5;/h6-7H,10H2,1-5H3;1H/t6-,7+;/s3
InChIKey
SDHKEUUZUMQSAD-UHQDPJPENA-N
SMILES
[C@H](C)(OC(C)(C)C)[C@H](N)C(=O)OC.Cl |&1:0,7,r|
CAS DataBase Reference
71989-43-0(CAS DataBase Reference)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FB05064
Product name
o-tert-Butyl-L-threoine methyl ester HCl
Packaging
25g
Price
$248
Updated
2021/12/16
Chem-Impex
Product number
03147
Product name
--Butyl-L-threonine methyl ester hydrochloride
Purity
≥ 99% (HPLC)
Packaging
5G
Price
$56.9
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB05064
Product name
o-tert-Butyl-L-threoine methyl ester HCl
Packaging
5G
Price
$71
Updated
2021/12/16
Activate Scientific
Product number
AS92429
Product name
O-tert-Butyl-L-threonine Methyl Ester Hydrochloride
Purity
95% ee
Packaging
5G
Price
$99
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB05064
Product name
o-tert-Butyl-L-threoine methyl ester HCl
Packaging
10g
Price
$124
Updated
2021/12/16
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H-THR(TBU)-OME HCL Chemical Properties,Usage,Production

Chemical Properties

White to off white powder

Uses

H-Thr(tBu)-OMe.HCl is a threonine derivative[1].

Synthesis

Take L-threonine methyl ester into the round bottom flask, add anhydrous ethanol and rotor in the round bottom flask, put the round bottom flask into the silicone oil heating furnace heating to 80 ??, when the liquid becomes uniform, add potassium hydroxide to the round bottom flask, the reaction for 1 hour the liquid from turbid to transparent, add tert-butyllithium, the liquid becomes transparent light yellow. Continue the reaction for 2 hours, the color of the liquid remained unchanged, thin-layer chromatography to detect the progress of the reaction, to be L-Threonine methyl ester reaction is complete to stop the reaction. After cooling to room temperature and filtering, a light yellow powder was obtained. In a round-bottomed flask, add anhydrous dioxane and rotor in a round-bottomed flask, L-threonine methyl ester suspended in dioxane solution, and acylation reaction with fluorenylmethoxycarbonyl azide, thin-layer chromatography to detect the progress of the reaction, to wait for the reaction of O-tert-butyl-L-threonine is complete after the reaction was stopped to obtain the crude O-tert-butyl-L-threonine methyl ester hydrochloride, extracted with ethyl acetate under the condition of pH 9-10 The crude O-tert-butyl-L-threonine methyl ester hydrochloride was extracted with ethyl acetate at pH 9-10 and refined by recrystallization.

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

H-THR(TBU)-OME HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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H-THR(TBU)-OME HCL Suppliers

Gill polypeptide biopharmaceutical (dalian) co., LTD
Tel
021-61263455 13167021076
Email
amy@glschina.com
Country
China
ProdList
9920
Advantage
58
SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD
Tel
0838-2809458 13350585791
Email
pharm@biots.cn
Country
China
ProdList
619
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8667
Advantage
57
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
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View Lastest Price from H-THR(TBU)-OME HCL manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
H-THR(TBU)-OME HCL 71989-43-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
2000
Release date
2025-04-22

71989-43-0, H-THR(TBU)-OME HCLRelated Search:


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  • methyl O-(1,1-dimethylethyl)-L-threoninate hydrochloride
  • Methyl O-(tert-butyl)-L-threoninate hydrochloride
  • L-Threonine, O-(1,1-dimethylethyl)-, methyl ester, hydrochloride (1:1)
  • H-Thr(tBu)-Ome. HC
  • Thr(OtBu)-Ome.HCl
  • 71989-43-0
  • Amino Acid Derivatives
  • Threonine
  • Specialty Synthesis
  • Peptide Synthesis
  • Amino Acid Derivatives
  • Peptide Synthesis
  • Threonine
  • Amino Acids
  • ADVANCED INT.