H-THR(TBU)-OME HCL
- Product Name
- H-THR(TBU)-OME HCL
- CAS No.
- 71989-43-0
- Chemical Name
- H-THR(TBU)-OME HCL
- Synonyms
- H-Thr(tBu);H-Thr(tBu)-OMe;Thr(OtBu)-Ome.HCl;L-Thr(tBu)-OMe·HCl;H-THR(TBU)-OME HCL;H-THR(BUT)-OME HCL;H-Thr(tBu)-Ome. HC;H-L-THR(TBU)-OME HCL;THREONINE(TBU)-OME HCL;H-THR(TBU)-OME HCL USP/EP/BP
- CBNumber
- CB3427653
- Molecular Formula
- C9H20ClNO3
- Formula Weight
- 225.71
- MOL File
- 71989-43-0.mol
H-THR(TBU)-OME HCL Property
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Solid
- color
- White to off-white
- BRN
- 4716005
- InChI
- InChI=1/C9H19NO3.ClH/c1-6(13-9(2,3)4)7(10)8(11)12-5;/h6-7H,10H2,1-5H3;1H/t6-,7+;/s3
- InChIKey
- SDHKEUUZUMQSAD-UHQDPJPENA-N
- SMILES
- [C@H](C)(OC(C)(C)C)[C@H](N)C(=O)OC.Cl |&1:0,7,r|
- CAS DataBase Reference
- 71989-43-0(CAS DataBase Reference)
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FB05064
- Product name
- o-tert-Butyl-L-threoine methyl ester HCl
- Packaging
- 25g
- Price
- $248
- Updated
- 2021/12/16
- Product number
- 03147
- Product name
- --Butyl-L-threonine methyl ester hydrochloride
- Purity
- ≥ 99% (HPLC)
- Packaging
- 5G
- Price
- $56.9
- Updated
- 2021/12/16
- Product number
- FB05064
- Product name
- o-tert-Butyl-L-threoine methyl ester HCl
- Packaging
- 5G
- Price
- $71
- Updated
- 2021/12/16
- Product number
- AS92429
- Product name
- O-tert-Butyl-L-threonine Methyl Ester Hydrochloride
- Purity
- 95% ee
- Packaging
- 5G
- Price
- $99
- Updated
- 2021/12/16
- Product number
- FB05064
- Product name
- o-tert-Butyl-L-threoine methyl ester HCl
- Packaging
- 10g
- Price
- $124
- Updated
- 2021/12/16
H-THR(TBU)-OME HCL Chemical Properties,Usage,Production
Chemical Properties
White to off white powder
Uses
H-Thr(tBu)-OMe.HCl is a threonine derivative[1].
Synthesis
Take L-threonine methyl ester into the round bottom flask, add anhydrous ethanol and rotor in the round bottom flask, put the round bottom flask into the silicone oil heating furnace heating to 80 ??, when the liquid becomes uniform, add potassium hydroxide to the round bottom flask, the reaction for 1 hour the liquid from turbid to transparent, add tert-butyllithium, the liquid becomes transparent light yellow. Continue the reaction for 2 hours, the color of the liquid remained unchanged, thin-layer chromatography to detect the progress of the reaction, to be L-Threonine methyl ester reaction is complete to stop the reaction. After cooling to room temperature and filtering, a light yellow powder was obtained. In a round-bottomed flask, add anhydrous dioxane and rotor in a round-bottomed flask, L-threonine methyl ester suspended in dioxane solution, and acylation reaction with fluorenylmethoxycarbonyl azide, thin-layer chromatography to detect the progress of the reaction, to wait for the reaction of O-tert-butyl-L-threonine is complete after the reaction was stopped to obtain the crude O-tert-butyl-L-threonine methyl ester hydrochloride, extracted with ethyl acetate under the condition of pH 9-10 The crude O-tert-butyl-L-threonine methyl ester hydrochloride was extracted with ethyl acetate at pH 9-10 and refined by recrystallization.
References
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368
H-THR(TBU)-OME HCL Preparation Products And Raw materials
Raw materials
Preparation Products
H-THR(TBU)-OME HCL Suppliers
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View Lastest Price from H-THR(TBU)-OME HCL manufacturers
- Product
- H-THR(TBU)-OME HCL 71989-43-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 2000
- Release date
- 2025-04-22