OXYTHIAMINE HYDROCHLORIDE

Product Name: OXYTHIAMINE HYDROCHLORIDE
CAS No.: 614-05-1
Chemical Name: OXYTHIAMINE HYDROCHLORIDE
Synonyms: OXYTHIAMINE HCL;Oxythiamine Chloride HCl;OXYTHIAMINE HYDROCHLORIDE;Oxametholone Hydrochloride;OXYTHIAMINE CHLORIDE HYDROCHLORIDE;hydroxythiaminechloridehydrochloride;OXYTHIAMINE CHLORIDE HCL CRYSTALLINE;hyl)-4-methyl-,chloride,monohydrochloride;Thiamine Impurity 19（Oxythiamine Chloride HCl）;Oxythiamine chloride hydrochloride, ≥95% (HPLC)
CBNumber: CB3428625
Molecular Formula: C12H17Cl2N3O2S
Formula Weight: 338.25
MOL File: 614-05-1.mol

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OXYTHIAMINE HYDROCHLORIDE Property

Melting point:: >190°C (subl.)
storage temp.: -20°C
solubility: DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Safety

WGK Germany: 3
RTECS: XJ7034100

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: O4000
Product name: Oxythiamine chloride hydrochloride
Purity: ≥95% (HPLC)
Packaging: 1g
Price: $50.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: O4000
Product name: Oxythiamine chloride hydrochloride
Purity: ≥95% (HPLC)
Packaging: 5g
Price: $156
Updated: 2024/03/01

Cayman Chemical

Product number: 29953
Product name: Oxythiamine (chloride hydrochloride)
Packaging: 1g
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 29953
Product name: Oxythiamine (chloride hydrochloride)
Packaging: 25g
Price: $479
Updated: 2024/03/01

Cayman Chemical

Product number: 29953
Product name: Oxythiamine (chloride hydrochloride)
Packaging: 5g
Price: $140
Updated: 2024/03/01

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OXYTHIAMINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

thiamine antagonist

Uses

Oxythiamine chloride hydrochloride is suitable for use:

as a reference standard for calibration curve generation in liquid chromatography-tandem mass spectrometry (LC-MS/MS) for oxythiamine pyrophosphate (OTPP) quantification in red blood cells
as a thiamine transport inhibitor in human mammary epithelial cells (HMEC) and breast cancer cell lines
in the synthesis of oxythiamineH picrolonate salt

Definition

ChEBI: A hydrochloride obtained by combining oxythiamine chloride with one molar equivalent of hydrochloric acid.

General Description

Oxythiamine is a thiamine antimetabolite and the source through diet is by consuming acidic thiamine rich foods.

Biochem/physiol Actions

Oxythiamine (OT) is a thiamine antagonist. It is a transketolase inhibitor and is employed to study anti-metastatic mechanisms, especially those involving metalloproteinases (MMP). It significantly sensitizes human hepatocellular carcinoma cells (HCC) to sorafenib, favoring tumor suppression.

OXYTHIAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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OXYTHIAMINE HYDROCHLORIDE Suppliers

China 29 Germany 2 India 2 Switzerland 1 United States 7 Global 41

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614-05-1, OXYTHIAMINE HYDROCHLORIDERelated Search:

OXYTHIAMINE HYDROCHLORIDE

5-(2-HYDROXYETHYL)-3-(4-HYDROXY-2-METHYL-5-PYRIMIDINYLMETHYL)-4-METHYLTHIAZOLIUM CHLORIDE

5-[2-HYDROXYETHYL]-3-[4-HYDROXY-2-METHYL-5-PYRIMIDINYLMETHYL]-4-METHYLTHIAZOLIUM CHLORIDE HYDROCHLORIDE

Oxametholone Hydrochloride

hydroxythiaminechloridehydrochloride

hyl)-4-methyl-,chloride,monohydrochloride

OXYTHIAMINE CHLORIDE HYDROCHLORIDE

OXYTHIAMINE HCL

OXYTHIAMINE HYDROCHLORIDE

OXYTHIAMINE CHLORIDE HCL CRYSTALLINE

5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]-2-methyl-1H-pyrimidin-6-one chloride hydrochloride

5-[[5-(2-hydroxyethyl)-4-methyl-thiazol-3-ium-3-yl]methyl]-2-methyl-1H-pyrimidin-6-one chloride hydrochloride

5-(2-Hydroxyethyl)-4-methyl-3-[(2-methyl-6-oxo-1,6-dihydro-5-pyrimidinyl)methyl]-1,3-thiazol-3-ium chloride hydrochloride (1:1:1)

5-(2-Hydroxyethyl)-4-methyl-3-((2-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)methyl)thiazol-3-ium chloride hydrochloride

Thiamine Impurity 19（Oxythiamine Chloride HCl）

Oxythiamine Chloride HCl

Oxythiamine chloride hydrochloride, ≥95% (HPLC)

614-05-1

C12H17Cl2N3O2S

C12H16ClN3O2SHCl

C12H16N3O2SClHCl

C12H16N3O2SClClH

Biochemistry

Vitamin Derivatives

Vitamins