OXYTHIAMINE HYDROCHLORIDE
- Product Name
- OXYTHIAMINE HYDROCHLORIDE
- CAS No.
- 614-05-1
- Chemical Name
- OXYTHIAMINE HYDROCHLORIDE
- Synonyms
- OXYTHIAMINE HCL;Oxythiamine Chloride HCl;OXYTHIAMINE HYDROCHLORIDE;Oxametholone Hydrochloride;OXYTHIAMINE CHLORIDE HYDROCHLORIDE;hydroxythiaminechloridehydrochloride;OXYTHIAMINE CHLORIDE HCL CRYSTALLINE;hyl)-4-methyl-,chloride,monohydrochloride;Thiamine Impurity 19(Oxythiamine Chloride HCl);Oxythiamine chloride hydrochloride, ≥95% (HPLC)
- CBNumber
- CB3428625
- Molecular Formula
- C12H17Cl2N3O2S
- Formula Weight
- 338.25
- MOL File
- 614-05-1.mol
OXYTHIAMINE HYDROCHLORIDE Property
- Melting point:
- >190°C (subl.)
- storage temp.
- -20°C
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
Safety
- WGK Germany
- 3
- RTECS
- XJ7034100
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- O4000
- Product name
- Oxythiamine chloride hydrochloride
- Purity
- ≥95% (HPLC)
- Packaging
- 1g
- Price
- $50.3
- Updated
- 2024/03/01
- Product number
- O4000
- Product name
- Oxythiamine chloride hydrochloride
- Purity
- ≥95% (HPLC)
- Packaging
- 5g
- Price
- $156
- Updated
- 2024/03/01
- Product number
- 29953
- Product name
- Oxythiamine (chloride hydrochloride)
- Packaging
- 1g
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 29953
- Product name
- Oxythiamine (chloride hydrochloride)
- Packaging
- 25g
- Price
- $479
- Updated
- 2024/03/01
- Product number
- 29953
- Product name
- Oxythiamine (chloride hydrochloride)
- Packaging
- 5g
- Price
- $140
- Updated
- 2024/03/01
OXYTHIAMINE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
thiamine antagonist
Uses
Oxythiamine chloride hydrochloride is suitable for use:
- as a reference standard for calibration curve generation in liquid chromatography-tandem mass spectrometry (LC-MS/MS) for oxythiamine pyrophosphate (OTPP) quantification in red blood cells
- as a thiamine transport inhibitor in human mammary epithelial cells (HMEC) and breast cancer cell lines
- in the synthesis of oxythiamineH picrolonate salt
Definition
ChEBI: A hydrochloride obtained by combining oxythiamine chloride with one molar equivalent of hydrochloric acid.
General Description
Oxythiamine is a thiamine antimetabolite and the source through diet is by consuming acidic thiamine rich foods.
Biochem/physiol Actions
Oxythiamine (OT) is a thiamine antagonist. It is a transketolase inhibitor and is employed to study anti-metastatic mechanisms, especially those involving metalloproteinases (MMP). It significantly sensitizes human hepatocellular carcinoma cells (HCC) to sorafenib, favoring tumor suppression.