ChemicalBook > CAS DataBase List > 7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL
7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL
- Product Name
- 7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL
- CAS No.
- 6632-09-3
- Chemical Name
- 7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL
- Synonyms
- AURORA 23227;AKOS BBS-00001111;OTAVA-BB BB7010150234;NSC57969 >=98% (HPLC);7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL;8-Quinolinol, 7-(1-piperidinylmethyl)-;7-(1-piperidinylmethyl)-8-hydroxyquinoline
- CBNumber
- CB3434857
- Molecular Formula
- C15H18N2O
- Formula Weight
- 242.32
- MOL File
- Mol file
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7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL Property
- Melting point:
- 194 °C
- Boiling point:
- 402.4±30.0 °C(Predicted)
- Density
- 1.202±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 5mg/mL, clear (warmed)
- pka
- 3.81±0.50(Predicted)
- form
- powder
- color
- white to beige
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML1863
- Product name
- NSC57969
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $102
- Updated
- 2023/01/07
Sigma-Aldrich
- Product number
- SML1863
- Product name
- NSC57969
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $376
- Updated
- 2022/05/15
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7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL Chemical Properties,Usage,Production
Biological Activity
NSC57969 is a MDR-selective compound th at exhibits a robust Pgp-dependent toxic activity across diverse cancer cell lines. NSC57969 shows profound toxicity against doxorubicin resistant Brca1-/-;p53-/- spontaneous mouse mammary carcinoma cells. NSC57969 eradicates P-glycoprotein expression in doxorubicin resistant brca1-/-;p53-/- spontaneous mouse mammary carcinoma, and MES-SA/Dx5 cells. However treatment of normal cells (hCMEC/D3 cells) with NSC57969 does not induce loss of Pgp.
7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL Preparation Products And Raw materials
Raw materials
Preparation Products
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7-(PIPERIDIN-1-YLMETHYL)QUINOLIN-8-OL Suppliers
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