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4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE

Product Name
4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE
CAS No.
63910-43-0
Chemical Name
4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE
Synonyms
AURORA KA-6685;4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE;5-chloro-4-methoxy-1H-pyridazin-6-one;3(2H)-Pyridazinone, 4-chloro-5-methoxy-;4-Chloro-5-methoxy-3(2H)-pyridazinone;4-chloro-5-methoxy-2,3-dihydropyridazin-3-one;4-Chloro-2,3-dihydro-5-methoxy-3-oxopyridazine;4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE ISO 9001:2015 REACH
CBNumber
CB3445170
Molecular Formula
C5H5ClN2O2
Formula Weight
160.56
MOL File
63910-43-0.mol
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4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE Property

Melting point:
225 °C(dec.)
Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder to crystal
pka
8.90±0.60(Predicted)
color 
White to Orange to Green
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C2972
Product name
4-Chloro-5-methoxy-3(2H)-pyridazinone
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$189
Updated
2025/07/31
TCI Chemical
Product number
C2972
Product name
4-Chloro-5-methoxy-3(2H)-pyridazinone
Purity
>98.0%(GC)(T)
Packaging
200mg
Price
$64
Updated
2025/07/31
TRC
Product number
C381765
Product name
4-Chloro-5-methoxypyridazin-3(2H)-one
Packaging
100mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
W7573
Product name
4-Chloro-5-methoxypyridazin-3(2H)-one
Packaging
1g
Price
$104
Updated
2021/12/16
SynQuest Laboratories
Product number
4H17-5-1G
Product name
4-Chloro-5-methoxypyridazin-3(2H)-one
Packaging
1g
Price
$200
Updated
2021/12/16
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4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE Chemical Properties,Usage,Production

Synthesis

932-22-9

124-41-4

63910-43-0

General procedure for the synthesis of 4-chloro-5-methoxypyridazin-3(2H)-one (10): to a solution of 4,5-dichloropyridazin-3(2H)-one (4.1 g, 24.8 mmol) in methanol (50 mL) was added sodium methanolate (2.6 g, 74.5 mmol). The reaction mixture was stirred at 80 °C overnight. Upon completion of the reaction, the mixture was concentrated under reduced pressure and purified by column chromatography [eluent: petroleum ether to petroleum ether/dichloromethane/methanol (10:1:1)] to afford the target product, 4-chloro-5-methoxypyridazin-3(2H)-one (10) (1.2 g, 30% yield), as a white solid. The procedure for the synthesis of 4-chloro-2-(2-chlorobenzyl)-5-methoxypyridazin-3(2H)-one (11) was not provided with complete information.

References

[1] Journal of Medicinal Chemistry, 2004, vol. 47, # 19, p. 4716 - 4730
[2] Patent: WO2015/143164, 2015, A1. Location in patent: Page/Page column 115
[3] Monatshefte fuer Chemie, 1989, vol. 120, p. 329 - 342

4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE Suppliers

SiChuang NanBu Honesty Technology Co., Ltd.
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0838-5675166 15883665058
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0838-5675535
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nbcxkj@126.com
Country
China
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
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24529
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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0573-85285100
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isenchem@163.com
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China
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Tetranov Biopharm
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13526569071
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sales@leadmedpharm.com
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China
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Adamas Reagent, Ltd.
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400-6009262 16621234537
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021-64823266
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chenyj@titansci.com
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China
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
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China
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42934
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China DongFan Chemical Co.,LTD
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86-0571-85151182
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86-0571-85151182
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China
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Jinan Trio PharmaTech Co., Ltd.
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0531-88811783
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+86 (531) 55696010 QQ 1762738062
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sales@trio-pharmatech.com
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China
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Chiba Pharmaceutical Science and technology Co, Ltd.
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0531-81313138 13066006660
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QQ: 3366077777
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chibapharm@foxmail.com
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China
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TOKYO CHEMICAL INDUSTRY CO., LTD.
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03-36680489
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03-3668-0520
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Sales-JP@TCIchemicals.com
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Japan
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View Lastest Price from 4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE manufacturers

Shanghai Rlavie Technology Co ltd
Product
4-chloro-5-methoxypyridazin-3(2H)-one 63910-43-0
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%minHPLC
Supply Ability
10kgs/month
Release date
2021-11-13
Career Henan Chemical Co
Product
4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE 63910-43-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-25
Nanjing jinheyou Trading Co., Ltd.
Product
4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE 63910-43-0
Price
US $0.00/g
Min. Order
1g
Purity
95%min
Supply Ability
20kg/month
Release date
2019-12-20

63910-43-0, 4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONERelated Search:


  • 4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE
  • AURORA KA-6685
  • 4-Chloro-2,3-dihydro-5-methoxy-3-oxopyridazine
  • 5-chloro-4-methoxy-1H-pyridazin-6-one
  • 4-Chloro-5-methoxy-3(2<i>H</i>)-pyridazinone
  • 4-chloro-5-methoxy-2,3-dihydropyridazin-3-one
  • 3(2H)-Pyridazinone, 4-chloro-5-methoxy-
  • 4-CHLORO-5-METHOXYPYRIDAZIN-3(2H)-ONE ISO 9001:2015 REACH
  • 63910-43-0
  • Pyrazines, Pyrimidines & Pyridazines
  • Pyrazines, Pyrimidines & Pyridazines