BOC-ALA-NH2

Product Name: BOC-ALA-NH2
CAS No.: 85642-13-3
Chemical Name: BOC-ALA-NH2
Synonyms: BOC-ALA-NH2;BOC-L-ALA-NH2;Boc-L-alamine;BOC-Beta-ala-NH2;Boc-L-alanine-NH2;Boc-L-alanine amide;N-Boc-L-alaninamide;N-Boc-L-alanine amide;N-Boc-L-alaninaMide, 96%;(Tert-Butoxy)Carbonyl Ala-NH2
CBNumber: CB3449370
Molecular Formula: C8H16N2O3
Formula Weight: 188.22
MOL File: 85642-13-3.mol

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BOC-ALA-NH2 Property

Melting point:: 124-125 °C
Boiling point:: 343.1±25.0 °C(Predicted)
Density: 1.081±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Soluble in water or 1% acetic acid
pka: 11.38±0.46(Predicted)
form: Solid
Appearance: White to off-white Solid
optical activity: -34.8°(C=0.01g/mI, CHCL3, 20°C, 589nm)
Water Solubility: Soluble in water or 1% acetic acid.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B630138
Product name: BOC-ALA-NH2
Packaging: 5g
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: 3316AC
Product name: Boc-Ala-NH2
Packaging: 1g
Price: $14
Updated: 2021/12/16

Iris Biotech GmbH

Product number: BAA5310
Product name: Boc-L-Ala-NH2
Packaging: 5G
Price: $74.25
Updated: 2021/12/16

AK Scientific

Product number: J55723
Product name: Boc-Ala-NH2
Packaging: 25g
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB72151
Product name: Boc-Ala-NH2
Packaging: 25g
Price: $137.5
Updated: 2021/12/16

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BOC-ALA-NH2 Chemical Properties,Usage,Production

Uses

N-Boc-L-alaninamide is used as pharmaceutical intermediate.

Synthesis

15761-38-3

78981-25-6

GENERAL STEPS: N-Boc-L-alanine (5.0 g, 26.4 mmol) was dissolved in anhydrous THF at -10 °C and triethylamine (3 mL, 21.12 mmol) and ethyl chloroformate (2.5 mL, 26.4 mmol) were added sequentially under stirring. The reaction mixture was continued to be stirred at this temperature for 1 hour. Subsequently, ammonia (NH3) was passed into the reaction system for 1.5 hours. The reaction mixture was brought to room temperature and stirred overnight. After completion of the reaction, the THF solvent was removed by distillation under reduced pressure. Saturated sodium chloride solution (40 mL) was added to the residue and extracted with ethyl acetate (5 x 40 mL). The organic phases were combined, washed with 0.5 M hydrochloric acid (2 x 30 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give N-Boc-D-alaninamide.

References

[1] Tetrahedron, 1999, vol. 55, # 42, p. 12301 - 12308
[2] Tetrahedron Letters, 2007, vol. 48, # 4, p. 603 - 607
[3] Synthetic Communications, 2013, vol. 43, # 7, p. 993 - 1006
[4] Bulletin of the Chemical Society of Japan, 1988, vol. 61, # 7, p. 2647 - 2648
[5] Tetrahedron Asymmetry, 2013, vol. 24, # 24, p. 1572 - 1575

BOC-ALA-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-ALA-NH2 Suppliers

China 98 Germany 2 India 2 Italy 1 United Kingdom 2 United States 10 Global 115

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

AF Biochem Co., Ltd.

Tel: +86-028-60911900 13540204019
Email: sales@afbiochem.com
Country: China
ProdList: 479
Advantage: 57

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 42446
Advantage: 60

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View Lastest Price from BOC-ALA-NH2 manufacturers

Career Henan Chemical Co

Product: BOC-ALA-NH2 85642-13-3
Price: US $2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: ask
Release date: 2018-12-19

85642-13-3, BOC-ALA-NH2Related Search:

N-(tert-Butoxycarbonyl)-L-alanine BOC-GLU-GLU-LEU-OME BOC-ALA-ALA-PNA BOC-GLN-ARG-ARG-AMC ACETATE SALT BOC-MET-LEU-PHE-OH N-T-BOC-LEU-GLY-ARG P-NITROANILIDE BOC-PHE-PHE-GLY-OH BOC-PRO-LEU-VAL-OME BOC-LEU-GLY-ARG-AMC ACETATE SALT BOC-ILE-GLY-OH BOC-ALA-ALA-OH BOC-GLU-LYS-LYS-MCA BOC-VAL-PRO-ARG-MCA BOC-PRO-PRO-OH BOC-PHE-SER-ARG-AMC ACETATE SALT BOC-VAL-PRO-ARG-AMC HCL BOC-VAL-LEU-LYS-AMC ACETATE BOC-HIS-NHNH2

BOC-Beta-ala-NH2

N-alpha-t-Butyloxycarbonyl-beta-alanine amide

N-t-Butyloxycarbonyl-L-alanine amide

Boc-L-alanine amide

BOC-L-ALA-NH2

BOC-ALA-NH2

N-tert-Butoxycarbonyl-L-alanine amide

tert-butyl (1S)-2-amino-1-methyl-2-oxoethylcarbamate

(S)-tert-Butyl(1-amino-1-oxopropan-2-yl)carbamate

N<sup>2</sup>-(tert-Butoxycarbonyl)-L-alaninamide

tert-butyl N-[(1S)-1-carbamoylethyl]carbamate

N-Boc-L-alanine amide

N-(tert-Butoxycarbonyl)alaninaMide

N-Boc-L-alaninaMide, 96%

Boc-L-alanine-NH2

tert-Butyl-N-(1-carbaMoylethyl)carbaMate

(Tert-Butoxy)Carbonyl Ala-NH2

Carbamic acid, N-[(1S)-2-amino-1-methyl-2-oxoethyl]-, 1,1-dimethylethyl ester

tert-butyl N-[(2S)-1-amino-1-oxopropan-2-yl]carbamate

Carbamic acid, [(1S)-2-amino-1-methyl-2-oxoethyl]-, 1,1-dimethylethylester

1,1-Dimethylethyl N-[(1S)-2-amino-1-methyl-2-oxoethyl]carbamate

N-tert-Butoxycarbonyl-L-alanine amid

Boc-L-alamine

N-Boc-L-alaninamide

tert-Butyl N-[(1S)-2-amino-1-methyl-2-oxoethyl]carbamate

85642-13-3