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DIBENZO(A,I)PYRENE

Product Name
DIBENZO(A,I)PYRENE
CAS No.
191-30-0
Chemical Name
DIBENZO(A,I)PYRENE
Synonyms
DBC;DBC-d7;db(a,1)p;Db(a,l)p;NSC 90324;ba51-090462;Ba 51-090462;NSC 90324-d7;Ba 51-090462-d7;DIBENZ(A,I)PYRENE
CBNumber
CB3451069
Molecular Formula
C24H14
Formula Weight
302.37
MOL File
191-30-0.mol
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DIBENZO(A,I)PYRENE Property

Melting point:
228.05°C
Boiling point:
378.4°C (rough estimate)
Density 
1.1762 (estimate)
refractive index 
1.9130 (estimate)
storage temp. 
2-8°C
solubility 
Chloroform (Very Slightly, Heated), Dichloromethane (Slightly, Heated)
color 
Yellow to Orange
BRN 
2054068
Stability:
Stable, but may be heat sensitive - keep cool. Combustible. Incompatible with strong oxidizing agents.
IARC
2A (Vol. Sup 7, 92) 2010
EPA Substance Registry System
Dibenzo[a,l]pyrene (191-30-0)
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Safety

Hazard Codes 
Xn,T
Risk Statements 
40-67-36/37/38-45-41-52/53
Safety Statements 
23-24/25-36/37-45-26-53-39-61
RIDADR 
2811
WGK Germany 
3
HazardClass 
6.1(b)
PackingGroup 
III
Hazardous Substances Data
191-30-0(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

H341Suspected of causing genetic defects

H350May cause cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ERD-051
Product name
Dibenzo[a,l]pyrene
Purity
vial of 25?mg, Cerilliant?
Packaging
25mg
Price
$185
Updated
2024/03/01
Sigma-Aldrich
Product number
BCR096
Product name
Dibenzo[a,l]pyrene
Purity
BCR
Packaging
100mg
Price
$1170
Updated
2024/03/01
TRC
Product number
D416945
Product name
Dibenzo[def,p]chrysene
Packaging
1mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD21528
Product name
Dibenzo[def,p]chrysene
Packaging
1mg
Price
$170
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
56687
Product name
Dibenzo[def,p]chrysene
Packaging
100mg
Price
$2000
Updated
2021/12/16
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DIBENZO(A,I)PYRENE Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

An active metabolite from inhalation and dermal exposure to polycyclic aromatics hydrocarbons in hot mix asphalt paving workers. DBC is the most potent tumorigen that has been identified to date. Dib enzo[def,p]chrysene (DBC) is a carcinogen and should be handled with appropriate caution.

Definition

ChEBI: Dibenzo[a,l]pyrene is an ortho- and peri-fused polycyclic arene. It has a role as a mutagen and a human metabolite.

General Description

Yellow odorless crystals or flakes. Water insoluble.

Air & Water Reactions

Dust/air mixtures may ignite and explode. Insoluble in water.

Reactivity Profile

Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic hydrocarbons, such as DIBENZO(A,I)PYRENE, and strong oxidizing agents. They can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), nitration, sulfonation, and the Friedel-Crafts reaction.

Safety Profile

Confirmed carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.

Carcinogenicity

Dibenzo[a,1]pyrene is a class 2B carcinogen according to the IARC, although recent data suggest that it is a 2A carcinogen. In mouse studies, it has been more potent than benzo[a]pyrene in skin, and in rat studies, it has been more potent than 7,12-dimethylbenz [a]anthracene in the mammary gland. Dibenzo[a,l]pyrene was tested for carcinogenicity in studies of single and repeated dermal application to mice, as well as several initiation–promotion studies on mouse skin; all studies gave positive results. Dibenzo[a,l] pyrene also induced oral cavity tumors when applied dermally to the tongue of hamsters and lung tumors in mice following intraperitoneal injection. In addition to lung tumors, dibenzo[a,l]pyrene induced hepatic tumors and a variety of tumors at other sites when administered intraperitoneally to newborn mice. Multiple tumor sites were also observed following intragastric application of dibenzo[a,l]pyrene in mice. Intramamillary administration to rats also yielded positive results. Furthermore, two studies on fish demonstrated that nonmammalian species are also susceptible to dibenzo[a,l]pyreneinduced tumorigenicity.The most active metabolite is the potent 11,12-dihydrodiol of dibenzo[a,1] pyrene.

DIBENZO(A,I)PYRENE Preparation Products And Raw materials

Raw materials

Preparation Products

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DIBENZO(A,I)PYRENE Suppliers

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191-30-0, DIBENZO(A,I)PYRENERelated Search:


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