ChemicalBook > CAS DataBase List > 1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Product Name
1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
CAS No.
474944-25-7
Chemical Name
1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonyms
C16-04:1 PC;BUTENOYL PAF;1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1-O-HEXADECYL-2-O-(2E-BUTENOYL)-SN-GLYCERYL-3-PHOSPHOCHOLINE
CBNumber
CB3456857
Molecular Formula
C28H56NO7P
Formula Weight
549.72
MOL File
Mol file
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1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Property

storage temp. 
Store at -20°C
solubility 
≤0.5mg/ml in DMSO;10mg/ml in dimethyl formamide
form 
solution in ethanol.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
60929
Product name
Butenoyl PAF
Purity
≥98%
Packaging
1mg
Price
$79
Updated
2024/03/01
Cayman Chemical
Product number
60929
Product name
Butenoyl PAF
Purity
≥98%
Packaging
5mg
Price
$351
Updated
2024/03/01
Cayman Chemical
Product number
60929
Product name
Butenoyl PAF
Purity
≥98%
Packaging
10mg
Price
$623
Updated
2024/03/01
Cayman Chemical
Product number
60929
Product name
Butenoyl PAF
Purity
≥98%
Packaging
50mg
Price
$2716
Updated
2024/03/01
ApexBio Technology
Product number
C5385
Product name
ButenoylPAF
Packaging
5mg(solution)
Price
$400
Updated
2021/12/16
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1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Usage,Production

Definition

ChEBI: PC(O-16:0/4:1) is a phosphatidylcholine O-20:1.

Biological Activity

butenoyl paf is a paf receptor agonist [1].platelet activating factor (paf), a phospholipid mediator of inflammation, is secreted by several cell types including arterial endothelial cells, and can activate polymorphonuclear leucocytes and monocytes via specific cell surface receptors. paf also stimulates the production of active oxygen species by human monocyte - derived macrophages. paf play important roles in a variety of pathophysiological states including acute allergy, inflammation, asthma, gastrointestinal ulceration, and toxic shock [1][2].butanoyl-paf and butenoyl paf are both products of the oxidative decomposition of 2-arachidonoyl phospholipids. although butenoyl paf is 10-fold less potent than paf as a paf receptor agonist and ligand, it is 100-fold more abundant in oxidized ldl than paf. therefore, oxidation products of ldl phospholipids were physiologically relevant bioactive paf-like molecules [1].

References

[1]. marathe gk, davies ss, harrison ka, et al. inflammatory platelet-activating factor-like phospholipids in oxidized low density lipoproteins are fragmented alkyl phosphatidylcholines. j biol chem. 1999 oct 1;274(40):28395-404.
[2]. davies ss, pontsler av, marathe gk, et al. oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists. j biol chem. 2001 may 11;276(19):16015-23.

1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Suppliers

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474944-25-7, 1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINERelated Search:


  • C16-04:1 PC
  • BUTENOYL PAF
  • 1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1-O-HEXADECYL-2-O-(2E-BUTENOYL)-SN-GLYCERYL-3-PHOSPHOCHOLINE
  • 474944-25-7